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Table 3 Multivariable mixed effect analysis of increase in number of failed organs in the first 28 days

From: Thrombomodulin is associated with increased mortality and organ failure in mechanically ventilated children with acute respiratory failure: biomarker analysis from a multicenter randomized controlled trial

Covariates

Estimate

SE

P value

Intercept sTM

2.77 E−3

5.21 E−4

 < 1.00 E−4

Slope sTM

1.00 E−2

3.01 E−3

9.00 E−4

Age (years)

2.96 E−2

6.40 E−3

 < 1.00 E−4

Sex (male)

4.80 E−2

7.37 E−2

0.51

Race (white)

7.15 E−3

8.50 E−2

0.93

PRISM-III Score

6.03 E−2

5.35 E−3

 < 1.00 E−4

  1. Slope of sTM was derived from up to three values of sTM collected within 5 days of enrollment for each patient. Intercept of sTM was derived from the slope. Patients with only one measurement of sTM were excluded. SE standard error. n = 386