Sepsis-2 | |||||||
---|---|---|---|---|---|---|---|
Parameter | Sensitivity [95%CI] | Specificity [95%CI] | PPV [95%CI] | NPV [95%CI] | LR + [95%CI] | LR − [95%CI] | AUC [95%CI] |
MDW | 0.75 [0.69–0.80] | 0.73 [0.70–0.75] | 0.36 [0.32–0.40] | 0.93 [0.92–0.95] | 2.76 [2.46–3.09] | 0.34 [0.28–0.43] | 0.81 [0.78–0.84] |
WBC | 0.69 [0.63–0.74] | 0.83 [0.81–0.85] | 0.45 [0.40–0.50] | 0.93 [0.91–0.94] | 4.00 [3.50–4.60] | 0.40 [0.30–0.50] | 0.76 [0.72–0.79] |
PCT | 0.45 [0.39–0.51] | 0.88 [0.86–0.90] | 0.44 [0.38–0.50] | 0.89 [0.87–0.90] | 3.80 [3.10–4.65-] | 0.62 [0.56–0.70] | 0.78 [0.75–0.81] |
CRP | 0.85 [0.80–0.88] | 0.72 [0.70–0.75] | 0.39 [0.35–0.43] | 0.96 [0.94–0.97] | 3.06 [2.76–3.39] | 0.21 [0.16–0.28] | 0.85 [0.83–0.87] |
MDW + WBC |  |  |  |  |  |  | 0.86 [0.84–0.88] |
MDW + PCT |  |  |  |  |  |  | 0.81 [0.78–0.84] |
MDW + CRP |  |  |  |  |  |  | 0.85 [0.82–0.87] |
MDW + WBC + PCT |  |  |  |  |  |  | 0.86 [0.84–0.89] |
MDW + WBC + CRP |  |  |  |  |  |  | 0.87 [0.85–0.89] |
Sepsis-3 | Â | Â | Â | Â | Â | Â | Â |
MDW | 0.81 [0.73–0.86] | 0.69 [0.67–0.72] | 0.22 [0.18–0.25] | 0.97 [0.96–0.98] | 2.63 [2.35–2.94] | 0.28 [0.20–0.39] | 0.82 [0.79–0.85] |
WBC | 0.49 [0.41–0.57] | 0.77 [0.74–0.79] | 0.18 [0.15–0.22] | 0.94 [0.92–0.95] | 2.10 [1.70–2.50] | 0.70 [0.60–0.80] | 0.65 [0.60–0.70] |
PCT | 0.60 [0.52–0.68] | 0.87 [0.85–0.89] | 0.33 [0.27–0.39] | 0.95 [0.94–0.96] | 4.63 [3.83–5.60] | 0.46 [0.37–0.56] | 0.84 [0.80–0.87] |
CRP | 0.89 [0.83–0.93] | 0.68 [0.66–0.71] | 0.23 [0.19–0.26] | 0.98 [0.97–0.99] | 2.79 [2.53–3.07] | 0.16 [0.10–0.26] | 0.85 [0.82–0.87] |
MDW + WBC |  |  |  |  |  |  | 0.83 [0.79–0.86] |
MDW + PCT |  |  |  |  |  |  | 0.82 [0.79–0.86] |
MDW + CRP |  |  |  |  |  |  | 0.85 [0.82–0.88] |
MDW + WBC + PCT |  |  |  |  |  |  | 0.83 [0.80–0.86] |
MDW + WBC + CRP |  |  |  |  |  |  | 0.85 [0.82–0.87] |