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Table 3 Hazard ratio for (A) continuous CCL14 and (B) CCL14 tertiles, unadjusted and adjusted for baseline serum creatinine and non-renal APACHE III score in a Cox regression model with CCL14 as a time-dependent covariate

From: External validation of urinary C–C motif chemokine ligand 14 (CCL14) for prediction of persistent acute kidney injury

Model HR (95% CI) P value
A. Urinary CCL14 concentration as a continuous variable in model
Unadjusted (CCL14 only) 1.67 (1.36–2.06) < 0.001
Adjusted for baseline serum creatinine 1.55 (1.24–1.93) < 0.001
Adjusted for baseline non-renal APACHE 1.51 (1.22–1.88) < 0.001
Adjusted for baseline serum creatinine and non-renal APACHE 1.41 (1.13–1.75) 0.003
Model Tertile 2 versus 1 Tertile 3 versus 1
HR (95% CI) P value HR (95% CI) P value
B. Urinary CCL14 concentration divided into tertiles and used as a categorical variable in model
Unadjusted (CCL14 only) 1.14 (0.61–2.13) 0.671 2.56 (1.46–4.50) 0.001
Adjusted for baseline serum creatinine 1.09 (0.58–2.02) 0.795 2.16 (1.20–3.88) 0.010
Adjusted for baseline non-renal APACHE 1.15 (0.62–2.14) 0.662 2.10 (1.18–3.75) 0.012
Adjusted for baseline serum creatinine and non-renal APACHE 1.15 (0.62–2.15) 0.651 1.83 (1.02–3.29) 0.043
  1. Model is for time to RRT and/or death within 90 days