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Fig. 2 | Critical Care

Fig. 2

From: Serum uric acid, disease severity and outcomes in COVID-19

Fig. 2

Prevalence and kinetics of low serum uric acid levels among patients hospitalized with COVID-19, in discovery and validation cohorts. a In the discovery cohort, the prevalence of hypouricemia was 1/122 (0.8%) under basal conditions, 13/192 (6.8%) at admission, 39/192 (20.3%) at the lowest uric acid level and 5/140 (3.6%) at discharge. b In the validation cohort, the prevalence of hypouricemia increased from 21/325 (6.5%) upon admission to 63/325 (19.4%) during hospitalization. Circles represent individual values and black lines medians. Histograms show the distribution of time from admission to onset of hypouricemia in both cohorts. P values calculated using a mixed-effects model considering repeated measures in individual patients. ***P < 0.001

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