From: Temporal patterns of organ dysfunction after severe trauma
Factor | All patients | Group 1 | Group 2 | Group 3 | Group 4 | Group 5 |
---|---|---|---|---|---|---|
N | 660 | 300 | 135 | 87 | 40 | 98 |
APACHE II, points | 15 (10–21) | 12 (9–15) | 14 (10–19) | 16 (11–21) | 23 (18–30) | 24 (21–29) |
Admission SOFA, points | 6.0 (4.0–10) | 4.0 (3.0–6.0) | 7.0 (5.0–9.0) | 8.0 (6.0–10) | 12 (9.0–15) | 11 (9.0–12) |
Infection | 284 (43%) | 29 (9.7%) | 79 (58%) | 79 (91%) | 34 (85%) | 63 (64%) |
Sepsis | 139 (21%) | 4 (1.3%) | 25 (18%) | 49 (56%) | 29 (72%) | 32 (33%) |
Days with CNS SOFA ≥ 3 | 0.0 (0.0–3.0) | 0.0 (0.0–0.0) | 0.0 (0.0–2.0) | 0.0 (0.0–4.0) | 4.0 (1.0–9.0) | 10 (4.0–17) |
Days with renal SOFA ≥ 3 | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 3.0 (1.0–14) | 0.0 (0.0–0.0) |
Days with cardiovascular SOFA ≥ 3 | 2.0 (0.0–5.0) | 0.0 (0.0–0.0) | 3.0 (0.0–5.0) | 6.0 (3.0–8.0) | 13 (6.5–16) | 8.5 (3.0–13) |
Days with liver SOFA ≥ 3 | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 1.0 (0.0–7.0) | 0.0 (0.0–0.0) |
Days with coagulation SOFA ≥ 3 | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–2.0) | 0.0 (0.0–0.0) |
Days with respiratory SOFA ≥ 3 | 0.0 (0.0–3.0) | 0.0 (0.0–0.0) | 1.0 (0.0–2.0) | 5.0 (2.0–8.0) | 7.0 (3.5–12) | 3.0 (1.0–8.0) |
Proportion of days CNS SOFA ≥ 3 | 22% | 7.3% | 15% | 14% | 44% | 78% |
Proportion of days with renal SOFA ≥ 3 | 3.2% | 0.3% | 1.1% | 3.4% | 36% | 1.5% |
Proportion of days with cardiovascular SOFA ≥ 3 | 31% | 15% | 34% | 36% | 66% | 60% |
Proportion of days with liver SOFA ≥ 3 | 1.5% | 0.0% | 0.4% | 1.4% | 18% | 1.1% |
Proportion of days with coagulation SOFA ≥ 3 | 1.1% | 0.5% | 0.7% | 0.4% | 11% | 0.0% |
Proportion of days with respiratory SOFA ≥ 3 | 18% | 4.4% | 17% | 32% | 45% | 35% |
Days on vasopressor therapy | 2.0 (0.0–5.0) | 0.0 (0.0–0.0) | 3.0 (0.0–5.0) | 6.0 (4.0–8.0) | 13 (6.5–16) | 8.5 (3.0–13) |
Days on mechanical ventilation | 3.0 (1.0–8.0) | 1.0 (0.0–2.0) | 5.0 (3.0–6.0) | 11.0 (8.0–14) | 16.5 (10–22) | 16 (5.0–23) |
Days on CRRT | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 4.0 (0.0–18) | 0.0 (0.0–0.0) |