From: Trajectories of depression in sepsis survivors: an observational cohort study
Mild recovered (n = 152) | Severe persistent (n = 27) | Severe recovery (n = 45) | Total (n = 224) | Missings no. (%) | p value | |
---|---|---|---|---|---|---|
Sociodemographics | ||||||
Age, years mean (SD) | 61.4 (14.3) | 58.8 (13.7) | 59.4 (12.2) | 64.0 (14.4) | 0 (0.0) | 0.367a |
Women, no. (%) | 47 (30.9) | 11 (40.7) | 12 (26.7) | 70 (31.3) | 0 (0.0) | 0.454b |
Married, no. (%) | 82 (53.9) | 18 (66.6) | 21 (46.7) | 121 (54.0) | 4 (1.8) | 0.184b |
Employed, no. (%) | 45 (30.2) | 6 (22.2) | 13 (28.9) | 64 (29.0) | 3 (1.3) | 0.702b |
Educational status | ||||||
< High school, no. (%) | 52 (34.2) | 7 (25.9) | 13 (28.9) | 72 (32.1) | 1 (0.4) | 0.782b |
University degree, no. (%) | 33 (14.7) | 2 (0.9) | 9 (4.0) | 44 (19.7) | 1 (0.4) | 0.744b |
Comorbidity measures | ||||||
Charlson comorbidity index, median (IQR) | 3.0 (3.0) | 3.0 (4.0) | 5.0 (5.0) | 3.0 (4.0) | 1 (0.4) | 0.085a |
Active smoking, no. (%) | 18 (12.9) | 6 (23.1) | 7 (17.1) | 31 (15.0) | 17 (7.6) | 0.640b |
Body mass index, median (IQR) | 26.9 (6.4) | 28.3 (6.5) | 25.7 (8.0) | 27.1 (6.7) | 6 (2.7) | 0.137a |
Psychiatric diagnosis before sepsisc, no. of patients (%) | 18 (11.8) | 9 (33.3) | 7 (15.6) | 34 (15.2) | 52 (23.2) | 0.061b |
Use of antidepressants before sepsisc, no. of patients (%) | 8 (5.4) | 4 (15.4) | 1 (2.3) | 13 (6.0) | 55 (24.6) | 0.130b |
Use of analgesics before sepsisc, no. of patients (%) | 23 (15.1) | 8 (29.6) | 7 (15.6) | 38 (17.0) | 55 (24.6) | 0.216b |
Intensive care measures | ||||||
Length of ICU stay, median (IQR), d | 26.0 (30.0) | 17.0 (20.0) | 28.5 (37.0) | 25.0 (31.0) | 18 (8.0) | 0.155a |
Mechanical ventilation, no. of patients (%) | 128 (84.8) | 22 (81.5) | 39 (86.7) | 189 (84.8) | 1 (0.4) | 0.839b |
Mechanical ventilation, number of days, if applicable, mean (SD) | 14.7 (16.2) | 7.6 (12.2) | 14.5 (19.0) | 13.7 (16.3) | 102 (45.5) | 0.649a |
Renal replacement therapy, no. of patients (%) | 39 (26.0) | 7 (25.9) | 14 (31.1) | 60 (27.0) | 2 (0.9) | 0.788b |
Use of sedatives, no. of patients (%) | 80 (79.2) | 10 (55.6) | 19 (73.1) | 109 (75.2) | 79 (35.3) | 0.098b |
Psychiatric diagnosis at ICU discharge, no. of patients, (%) | 28 (19.3) | 7 (26.9) | 6 (13.6) | 50 (18.0) | 9 (4.0) | 0.435b |