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Table 1 Clinical characteristics of patients at the time of study admission (day 1 of intensive care unit stay) for the entire cohort and for the two sub-groups “sepsis” and “no-sepsis”

From: Serial measurement of pancreatic stone protein for the early detection of sepsis in intensive care unit patients: a prospective multicentric study

Variable Modality/statistics Total (N = 243) No Sepsis (N = 190) Sepsis (N = 53) p value
Gender F 90/243 (37%) 77/190 (41%) 13/53 (25%) 0.0331
M 153/243 (63%) 113/190 (59%) 40/53 (75%)
Age Median (Q1;Q3) 65.0 (54.0;73.0) 65 (54;72) 64 (55;73) 0.9152
SOFA score Median (Q1;Q3) 6 (5;9) 6 (4;9) 7 (5;9) 0.0402
Charlson score 0 51/243 (21%) 46/190 (24%) 5/53 (9%) 0.0551
1–2 84/243 (35%) 60/190 (32%) 24/53 (45%)
3–4 47/243 (19%) 34/190 (18%) 13/53 (25%)
5 and more 52/243 (21%) 42/190 (22%) 10/53 (19%)
Non-reported Charlson score 9/243 (4%) 8/190 (4%) 1/53 (2%)
Reason for ICU admission CNS (trauma, stroke, haemorrhage) 94/243 (39%) 74/190 (39%) 20/53 (38%) 0.6573
Cardiovascular 76/243 (31%) 60/190 (32%) 16/53 (30%)
Abdominal/digestive 45/243 (19%) 32/190 (17%) 13/53 (25%)
Respiratory 18/243 (7%) 16/190 (8%) 2/53 (4%)
Metabolic 9/243 (4%) 7/190 (4%) 2/53 (4%)
ICU treatments Mechanical ventilation 187/243 (77%) 143/190 (75%) 44/53 (83%) 0.2361
Vasopressors 95/243 (39%) 69/190 (36%) 26/53 (49%) 0.1751
No-reported vasopressors 16/243 (7%) 15/190 (8%) 1/53 (2%)  
Comorbidities Cancer 40/243 (16%) 33/190 (17%) 7/53 (13%) 0.4301
Heart disease 35/243 (14%) 26/190 (14%) 9/53 (17%) 0.5901
Pulmonary disease 31/243 (13%) 26/190 (14%) 5/53 (9%) 0.3811
Renal disease 29/243 (12%) 23/190 (12%) 6/53 (11%) 0.8321
Liver disease 17/243 (7%) 12/190 (6%) 5/53 (9%) 0.5433
ICU length of stay Median (Q1;Q3) 9 (6;17) 7 (5;13) 21 (14;27) < 0.0012
  1. The following tests were performed: 1Chi2; 2Wilcoxon; 3Fisher’s exact. Statistical significance was set a p value ≤ 0.05
  2. ICU intensive care unit, IQR interquartile range, SOFA sequential organ failure assessment, CNS central nervous system