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Table 1 Clinical characteristics of patients at the time of study admission (day 1 of intensive care unit stay) for the entire cohort and for the two sub-groups “sepsis” and “no-sepsis”

From: Serial measurement of pancreatic stone protein for the early detection of sepsis in intensive care unit patients: a prospective multicentric study

Variable

Modality/statistics

Total (N = 243)

No Sepsis (N = 190)

Sepsis (N = 53)

p value

Gender

F

90/243 (37%)

77/190 (41%)

13/53 (25%)

0.0331

M

153/243 (63%)

113/190 (59%)

40/53 (75%)

Age

Median (Q1;Q3)

65.0 (54.0;73.0)

65 (54;72)

64 (55;73)

0.9152

SOFA score

Median (Q1;Q3)

6 (5;9)

6 (4;9)

7 (5;9)

0.0402

Charlson score

0

51/243 (21%)

46/190 (24%)

5/53 (9%)

0.0551

1–2

84/243 (35%)

60/190 (32%)

24/53 (45%)

3–4

47/243 (19%)

34/190 (18%)

13/53 (25%)

5 and more

52/243 (21%)

42/190 (22%)

10/53 (19%)

Non-reported Charlson score

9/243 (4%)

8/190 (4%)

1/53 (2%)

Reason for ICU admission

CNS (trauma, stroke, haemorrhage)

94/243 (39%)

74/190 (39%)

20/53 (38%)

0.6573

Cardiovascular

76/243 (31%)

60/190 (32%)

16/53 (30%)

Abdominal/digestive

45/243 (19%)

32/190 (17%)

13/53 (25%)

Respiratory

18/243 (7%)

16/190 (8%)

2/53 (4%)

Metabolic

9/243 (4%)

7/190 (4%)

2/53 (4%)

ICU treatments

Mechanical ventilation

187/243 (77%)

143/190 (75%)

44/53 (83%)

0.2361

Vasopressors

95/243 (39%)

69/190 (36%)

26/53 (49%)

0.1751

No-reported vasopressors

16/243 (7%)

15/190 (8%)

1/53 (2%)

 

Comorbidities

Cancer

40/243 (16%)

33/190 (17%)

7/53 (13%)

0.4301

Heart disease

35/243 (14%)

26/190 (14%)

9/53 (17%)

0.5901

Pulmonary disease

31/243 (13%)

26/190 (14%)

5/53 (9%)

0.3811

Renal disease

29/243 (12%)

23/190 (12%)

6/53 (11%)

0.8321

Liver disease

17/243 (7%)

12/190 (6%)

5/53 (9%)

0.5433

ICU length of stay

Median (Q1;Q3)

9 (6;17)

7 (5;13)

21 (14;27)

< 0.0012

  1. The following tests were performed: 1Chi2; 2Wilcoxon; 3Fisher’s exact. Statistical significance was set a p value ≤ 0.05
  2. ICU intensive care unit, IQR interquartile range, SOFA sequential organ failure assessment, CNS central nervous system