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Table 2 Clinical characteristics of patients with COVID-19 with ARDS according to status at D28

From: Longitudinal assessment of IFN-I activity and immune profile in critically ill COVID-19 patients with acute respiratory distress syndrome

  Survivors (n = 26) Non-survivors (n = 14) p value
Demographics
 Age 65 [55–70] 67 [58–78] 0.3076
 Gender 23 (88%) 13 (93%) > 0.9999
 Body mass index (kg/m2) 30 [27–35] 28 [24–30] 0.0960
 Body mass index > 30 kg/m2 14 (54%) 3 (21%) 0.0921
 Delay between first symptoms (Days) 7 [4–12] 5 [4–9] 0.1909
Comorbidities
 Comorbidities    0.3202
  0 15 (58%) 5 (36%)  
  ≥ 1 11 (42%) 9 (64%)  
 Charlson score 0 [0–2] 2 [0–2] 0.1281
Severity scores
 SOFA score 8 [3–10] 8 [4–8] 0.7937
 SAPS II score 41 [31–52] 40 [33–59] 0.5893
 PaO2/FiO2 at admission 150 [94–169] 116 [94–162] 0.2993
 ARDS severity mild 1 (4%) 1 (7%) > 0.9999
 Moderate 18 (69%) 9 (64%) > 0.9999
 Severe 7 (27%) 4 (29%) > 0.9999
Follow-up
 Days in ICU 40 [16–76] 11 [6–20] 0.0008
 Days in hospital 64 [38–77] 15 [7–20] < 0.0001
 Secondary infections 21 (81%) 9 (64%) 0.2777
  1. The results are shown as medians and interquartile ranges [Q1–Q3] for continuous variables or numbers and percentage for categorical variables. COVID-19 patients with ARDS were separated in two groups based on status at D28 after admission. Sepsis-related organ failure assessment (SOFA) and simplified acute physiology score II (SAPS II) scores were calculated during the first 24 h after admission. Patients were classified in ARDS severity groups according to Berlin criteria. ICU: intensive care unit. Data were compared using nonparametric Mann–Whitney test for continuous variables or Fisher’s exact test for categorical variables
  2. p values inferior to 0.05 are highlighted in bold