|
Survivors (n = 26)
|
Non-survivors (n = 14)
|
p value
|
---|
Demographics
|
Age
|
65 [55–70]
|
67 [58–78]
|
0.3076
|
Gender
|
23 (88%)
|
13 (93%)
|
> 0.9999
|
Body mass index (kg/m2)
|
30 [27–35]
|
28 [24–30]
|
0.0960
|
Body mass index > 30 kg/m2
|
14 (54%)
|
3 (21%)
|
0.0921
|
Delay between first symptoms (Days)
|
7 [4–12]
|
5 [4–9]
|
0.1909
|
Comorbidities
|
Comorbidities
| | |
0.3202
|
0
|
15 (58%)
|
5 (36%)
| |
≥ 1
|
11 (42%)
|
9 (64%)
| |
Charlson score
|
0 [0–2]
|
2 [0–2]
|
0.1281
|
Severity scores
|
SOFA score
|
8 [3–10]
|
8 [4–8]
|
0.7937
|
SAPS II score
|
41 [31–52]
|
40 [33–59]
|
0.5893
|
PaO2/FiO2 at admission
|
150 [94–169]
|
116 [94–162]
|
0.2993
|
ARDS severity mild
|
1 (4%)
|
1 (7%)
|
> 0.9999
|
Moderate
|
18 (69%)
|
9 (64%)
|
> 0.9999
|
Severe
|
7 (27%)
|
4 (29%)
|
> 0.9999
|
Follow-up
|
Days in ICU
|
40 [16–76]
|
11 [6–20]
|
0.0008
|
Days in hospital
|
64 [38–77]
|
15 [7–20]
|
< 0.0001
|
Secondary infections
|
21 (81%)
|
9 (64%)
|
0.2777
|
- The results are shown as medians and interquartile ranges [Q1–Q3] for continuous variables or numbers and percentage for categorical variables. COVID-19 patients with ARDS were separated in two groups based on status at D28 after admission. Sepsis-related organ failure assessment (SOFA) and simplified acute physiology score II (SAPS II) scores were calculated during the first 24 h after admission. Patients were classified in ARDS severity groups according to Berlin criteria. ICU: intensive care unit. Data were compared using nonparametric Mann–Whitney test for continuous variables or Fisher’s exact test for categorical variables
- p values inferior to 0.05 are highlighted in bold