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Fig. 3 | Critical Care

Fig. 3

From: Longitudinal assessment of IFN-I activity and immune profile in critically ill COVID-19 patients with acute respiratory distress syndrome

Fig. 3

Immune response in COVID-19 ARDS patients according to status at D28. Immune parameters were measured 5 times (D0: within the first 48 h, D3: between day3 and D4, D7: between D7 and D9, D12: between D12 and D15, D20: between D20 and D25) during the first month after ICU admission in COVID-19 patients with ARDS. Patients were stratified in two groups according to their status at D28: survivors (n = 26) or non-survivors (n = 14). Over time evolution of immune parameters during the first month after admission in survivors (grey boxes) and non-survivors (red boxes) is shown. Regarding plasma IFNα2 level, in one non-survivor patient at D0 and in one survivor patient at D7, plasma IFNα2 concentration were null and could not be plotted. Data are presented as Tukey box-plots and individual values. Nonparametric Mann–Whitney test was used to compare values between groups at the same time point. Only p values below 0.05 are shown. The results were not adjusted for multiple test comparisons

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