Fig. 4From: Negative drift of sedation depth in critically ill patients receiving constant minimum alveolar concentration of isoflurane, sevoflurane, or desflurane: a randomized controlled trialThe bootstrapped regression’s mean coefficients per group (slope and intercept) are displayed as blue lines. The horizontal axis is the duration of uninterrupted volatile sedation; the vertical axis is the EEG-derived sedation depth. Below the dotted red line, it is considered excessive sedation (stage E and F)Back to article page