From: Implications of cardiac markers in risk-stratification and management for COVID-19 patients
 | Total (N = 2954) | Mild/Moderate (N = 1439) | Severe/Critical (N = 1515) | P value |
---|---|---|---|---|
Characteristics | ||||
Age (yr.)—median (Interquartile range [IQR]) | 60 (50–68) | 57(45–65) | 63 (54–71) |  < 0.001 |
Sex– no. (%) | – | – | – | 1 |
 Male | 1,493 (50.5%) | 728 (50.6%) | 765 (50.5%) |  |
 Female | 1,461 (49.5%) | 711 (49.4%) | 750 (49.5%) |  |
Initial temperature (℃) – median (IQR) | – | – | – | 0.002 |
  ≤ 37.3– no. (%) | 2,833 (95.9%) | 1,398 (97%) | 1,435 (94.7%) | – |
 37.3–38– no. (%) | 85 (2.9%) | 25 (2%) | 60 (4%) | – |
 38 -39– no. (%) | 35 (1.17%) | 16 (1%) | 19(1.2%) | – |
  > 39– no. (%) | 1 (0.03%) | 0 (0%) | 1 (0.1%) | – |
Comorbidities—no. (%) | ||||
 Hypertension | 889 (30%) | 348 (24%) | 541 (36%) |  < 0.001 |
 Diabetes | 401 (14%) | 159 (11%) | 242 (16%) |  < 0.001 |
 Cardiovascular disease | 330 (11%) | 104 (7%) | 226 (15%) |  < 0.001 |
 Cerebrovascular disease | 118 (4%) | 34 (2%) | 84 (6%) |  < 0.001 |
 Cancer | 74 (3%) | 19 (1%) | 55 (4%) |  < 0.001 |
 Chronic obstructive pulmonary disease | 139 (5%) | 40 (3%) | 99 (7%) |  < 0.001 |
 Chronic renal disease | 47 (2%) | 14 (1%) | 33 (2%) | 0.012 |
 Chronic liver disease | 76 (3%) | 36 (3%) | 40 (3%) | 0.817 |
 Immunodeficiency | 9 (0%) | 4 (0%) | 5 (0%) | 1 |
Respiratory rate—median (IQR) | – | – | – |  < 0.001 |
  > 24 breaths per min– no. (%) | 132 (4%) | 14 (1%) | 118 (8%) | – |
  ≤ 24 breaths per min–no. (%) | 2,820 (95%) | 1,425 (99%) | 1,395 (92%) | – |
Hospital stays—median (IQR) | 13 (8–19) | 12 (8–17) | 14 (8–22) |  < 0.001 |
Death—no. (%) | 59(2%) | 0 (0%) | 59(4%) |  < 0.001 |
Clinical symptoms—no. (%) | ||||
 Fever | 2,149 (73%) | 1,032 (72%) | 1,117 (74%) | 0.231 |
 Cough | 2,062 (70%) | 992 (69%) | 1,070 (71%) | 0.336 |
 Shortness of breath | 1302 (44%) | 608 (42%) | 694 (46%) | 0.05 |
 Chest tightness | 1,137 (38%) | 517 (36%) | 620 (41%) | 0.006 |
 Fatigue | 669 (23%) | 279 (19%) | 390 (26%) |  < 0.001 |
 Muscle soreness | 118 (4%) | 29 (2%) | 89 (6%) |  < 0.001 |
 Headache | 17 (1%) | 13 (1%) | 4 (0%) | 0.027 |
 Dizziness | 26 (1%) | 14 (1%) | 12 (1%) | 0.695 |
 Nausea | 22 (1%) | 12 (1%) | 10 (1%) | 0.671 |
 Vomiting | 22 (1%) | 11 (1%) | 11 (1%) | 1 |
 Diarrhea | 64 (2%) | 34 (2%) | 30 (2%) | 0.528 |
Radiological findings (N = 2567)—no. (%) | ||||
 Blurred edges | 304 (12%) | 118 (9.6%) | 186 (14%) |  < 0.001 |
 Lymph node enlargement | 30 (1.2%) | 18 (1.5%) | 12 (0.9%) | 0.202 |
 Ground glass opacity | 2324 (91%) | 1109 (90%) | 1215 (91%) | 0.304 |
 Cystic change | 209 (8.2%) | 81 (6.6%) | 128 (9.6%) | 0.006 |
 Airway obstruction | 4 (0.16%) | 2 (0.16%) | 2 (0.15%) | 1 |
 Consolidation | 332 (13%) | 115 (9.4%) | 217 (16%) |  < 0.001 |
 Fine reticular opacity | 56 (2.2%) | 17 (1.4%) | 39 (2.9%) | 0.01 |
 Lung texture increase | 1529 (60%) | 734 (60%) | 795 (60%) | 0.968 |
 Intralobular septal thickening | 14 (0.55%) | 4 (0.33%) | 10 (0.75%) | 0.183 |
 Pleural thickening | 221 (8.6%) | 72 (5.9%) | 149 (11%) |  < 0.001 |
 Pleural effusion | 205 (8%) | 34 (2.8%) | 171 (13%) |  < 0.001 |
 Bronchiectasis | 53 (2.1%) | 17 (1.4%) | 36 (2.7%) | 0.025 |
Viral load of throat swabs (N = 1476)—median (IQR) | ||||
 ORF1ab | 37.7 (34.51–40.08) | 37.85 (34.85–40.05) | 37.62 (34.07–40.15) | 0.258 |
N | 36.33 (33.77–37.82) | 36.4 (34.08–37.77) | 36.28 (33.5–37.91) | 0.762 |
Anti-SARS-Cov-2 IgG and IgM level—median (IQR) | ||||
 IgG level | 139.49 (73.93–181.24) | 141.33 (74.82–180.45) | 137.64 (73.88–181.45) | 0.864 |
 IgM level | 26.88 (8.38–66.74) | 26.46 (8.13–62.5) | 27.32 (8.52–68.62) | 0.337 |