Fig. 7From: Urinary metabolites predict mortality or need for renal replacement therapy after combat injurySimplified de novo NAD+ and NAD+ salvage pathways. De novo pathway (blue arrows) makes NAD+ from tryptophan and quinolinate. The salvage pathway (green arrows) makes NAD+ from nicotinamide and nicotinamide mononucleotide. 1-methylnicotinamide is a by-product of the salvage pathway. Adapted from reference [21]Back to article page