Table 1 Number of patients and ventilation characteristics described in the included studies
From: Mechanical ventilation parameters in critically ill COVID-19 patients: a scoping review
Study | Sample size, no. | Tidal volume ml/kg | Respiratory rate breath/min | PEEP cmH2O | Plateau pressure cmH2O | Driving pressure cmH2O | Crs mL/cmH2O | Mechanical power J/min | FiO2% | PaO2/FiO2 ratio mmHg | PaCO2 mmHg |
|---|---|---|---|---|---|---|---|---|---|---|---|
Schmidt [17] | 4643 | 6.1 [5.8–6.7] | 12 [10–14] | 24 [21–27] | 13 [10–17] | 33 [26–42] | 26.5 [19–35] | 154 [106–223] | 40 [35–46] | ||
Grasselli [22] | 3988 | 13 [10–15] | 70 [60–85] | 145 [103–203] | |||||||
Gupta [21] | 2215 | 12 [10–15] | 80 [60–100] | 124 [86–188] | |||||||
Ferrando [19] | 742 | 6.9 [6.3–7.8] | 24 [20–30] | 12 [11–14] | 25 [22–29] | 12 [10–16] | 35 [27–45] | 80 [60–100] | 120 [83–177] | 45 [37–55] | |
Botta [23] | 553 | 6.3 [5.7–7.1] | 20 [18–24] | 14 [11–15] | 14 [11–16] | 31.9 [26–39.9] | 17.7 [14–22] | 60 [50–80] | 159 [129–201] | 44 [38–51] | |
Grasselli [18] | 301 | 7 [6.3–7.6] | 20 [18–24] | 13 [10–15] | 24 [22–26] | 11 [9–14] | 41 [33–52] | 16.8 [14–21] | 60 [50–80] | 124 [89–164] | 46 [40–53] |
Schenck [26] | 267 | 7.01 [6.13–8.1] | 10 [8–12] | 25 [21–29] | 14 [11–17] | 28 [23–38] | 103 [82–134] | 44 [38–52] | |||
Cummings [20] | 257 | 6.2 [5.9–7.2] | 15 [12–18] | 27 [23–31] | 15 [11–18] | 27 [22–36] | 100 [80–100] | 129 [80–203] | |||
Roedl [24] | 223 | 22 [20–28] | 12 [10–15] | 60 [50–80] | |||||||
Auld [25] | 217 | 34 [28–46] | 132 [100–178] | ||||||||
Mitra [8] | 117 | 12 [10–14] | 22 [20–24] | 35 [31–44] | 50 [40–60] | 180 [148–216] | |||||
Pandya [35] | 75 | 10.3 (3.9) | 24.4 (6.7) | 14.3 (6.1) | 37.8 (21.9) | 62 (32) | 162 [106–316] | ||||
Cavayas [41] | 75 | 7.5 [6.8–8.7] | 20 [16–22] | 9 [8–10] | 21 [19–24] | 13 [10–16] | 48 [38–58] | 20.3 [16–28] | 50 [40–65] | 177 [138–276] | 44 [40–49] |
Zangrillo [36] | 73 | 6.7 [6–7.5] | 12 [10–14] | 12 [7–16.5] | 70 [52–80] | 110 [80–158.5] | 46.4 [40.0–51.3] | ||||
Ziehr [28] | 66 | 10 [8–12] | 21 [19–26] | 11 [9–12] | 35 [30–43] | 182 [135–245] | |||||
Sinha [27] | 39 | 12 [6–20] | 31 [27–34] | 24 [20–28] | 135 [113–158] | ||||||
Laverdure [37] | 36 | 6.1 (0.6) | 25 [24–27] | 13.4 (3.2) | 39.4 (16.9) | 65 [50–100] | 152 [112–240] | ||||
Bos [34] | 38 | 10 [9–12] | 20.5 [17–23] | 10.5 [7–13] | 49 (24.5) | 131.8 [47.9] | |||||
Haudebourg [30] | 30 | 6 [5.9–6.7] | 28 [28–30] | 10 [8–12] | 21 [20–24] | 10 [8–12] | 44 [35–51] | 70 [52–80] | 119 [97–163] | ||
Beloncle [31] | 25 | 6.0 [5.9–6.1] | 28 [26–30] | 12 [10–15] | 23 [21–24] | 60 [40–65] | 135 [119–195] | 41 [38–44] | |||
Bhatraju [29] | 24 | 25 [20–28] | 13 [11–17] | 29 [25–36] | 90 [70–100] | 142 [94–177] | |||||
Diehl [32] | 22 | 33 [28.5–35] | 16.5 [16–18] | 27 [25–28] | 9.5 [9–11.75] | 39.5 [33–45] | 45 [40–58] | 198 [167–298] | 55 [44–62] | ||
Pedersen [38] | 17 | 5.6 (1) | 62 (20) | 44.2 (8.2) | |||||||
Roesthuis [33] | 14 | 24 (3) | 11 (2) | 42 (3) | 57 (15) | 162 (48) | 57 (13) | ||||
Carsetti [39] | 10 | 14 (1,49) | 24 (2) | 9.5 (3) | 49 (9) | 70 (0.18) | 119 (33.6) | ||||
Liu X [40] | 8 | 7.5 (0.6) | 20.1 (1.5) | 9.6 (1.2) | 23.6 (3) | 14 (2.5) | 33.9 (7.6) | 102 (27.9) | 41.8 (3.7) | ||
LUNG SAFE [50] | 2377 | 7.6 [7.5–7.7] | 20.8 [21.2–21.5] | 8.4 [8.3–8.6] | 23.2 [23, 24] | 32 [25–43] | 0.65 [0.64–0.65] | 161 [158–163] | 46 [45.4–46.6] |