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Table 1 Number of patients and ventilation characteristics described in the included studies

From: Mechanical ventilation parameters in critically ill COVID-19 patients: a scoping review

Study Sample size, no. Tidal volume ml/kg Respiratory rate breath/min PEEP cmH2O Plateau pressure cmH2O Driving pressure cmH2O Crs mL/cmH2O Mechanical power J/min FiO2% PaO2/FiO2 ratio mmHg PaCO2 mmHg
Schmidt [17] 4643 6.1
[5.8–6.7]
  12
[10–14]
24
[21–27]
13
[10–17]
33
[26–42]
26.5
[19–35]
  154
[106–223]
40
[35–46]
Grasselli [22] 3988    13
[10–15]
     70
[60–85]
145
[103–203]
 
Gupta [21] 2215    12
[10–15]
     80
[60–100]
124
[86–188]
 
Ferrando [19] 742 6.9
[6.3–7.8]
24
[20–30]
12
[11–14]
25
[22–29]
12
[10–16]
35
[27–45]
  80
[60–100]
120
[83–177]
45
[37–55]
Botta [23] 553 6.3
[5.7–7.1]
20
[18–24]
14
[11–15]
  14
[11–16]
31.9
[26–39.9]
17.7
[14–22]
60
[50–80]
159
[129–201]
44
[38–51]
Grasselli [18] 301 7
[6.3–7.6]
20
[18–24]
13
[10–15]
24
[22–26]
11
[9–14]
41
[33–52]
16.8
[14–21]
60
[50–80]
124
[89–164]
46
[40–53]
Schenck [26] 267 7.01
[6.13–8.1]
  10
[8–12]
25
[21–29]
14
[11–17]
28
[23–38]
   103
[82–134]
44
[38–52]
Cummings [20] 257 6.2
[5.9–7.2]
  15
[12–18]
27
[23–31]
15
[11–18]
27
[22–36]
  100
[80–100]
129
[80–203]
 
Roedl [24] 223   22
[20–28]
12
[10–15]
     60
[50–80]
  
Auld [25] 217       34
[28–46]
   132
[100–178]
 
Mitra [8] 117    12
[10–14]
22
[20–24]
  35
[31–44]
  50
[40–60]
180
[148–216]
 
Pandya [35] 75    10.3
(3.9)
24.4
(6.7)
14.3
(6.1)
37.8
(21.9)
  62
(32)
162
[106–316]
 
Cavayas [41] 75 7.5
[6.8–8.7]
20
[16–22]
9
[8–10]
21
[19–24]
13
[10–16]
48
[38–58]
20.3
[16–28]
50
[40–65]
177
[138–276]
44
[40–49]
Zangrillo [36] 73 6.7
[6–7.5]
  12
[10–14]
  12
[7–16.5]
   70
[52–80]
110
[80–158.5]
46.4
[40.0–51.3]
Ziehr [28] 66    10
[8–12]
21
[19–26]
11
[9–12]
35
[30–43]
   182
[135–245]
 
Sinha [27] 39    12
[6–20]
31
[27–34]
  24
[20–28]
   135
[113–158]
 
Laverdure [37] 36 6.1
(0.6)
25
[24–27]
13.4
(3.2)
   39.4
(16.9)
  65
[50–100]
152
[112–240]
 
Bos [34] 38    10
[9–12]
20.5
[17–23]
10.5
[7–13]
49
(24.5)
   131.8
[47.9]
 
Haudebourg [30] 30 6
[5.9–6.7]
28
[28–30]
10
[8–12]
21
[20–24]
10
[8–12]
44
[35–51]
  70
[52–80]
119
[97–163]
 
Beloncle [31] 25 6.0
[5.9–6.1]
28
[26–30]
12
[10–15]
23
[21–24]
    60
[40–65]
135
[119–195]
41
[38–44]
Bhatraju [29] 24     25
[20–28]
13
[11–17]
29
[25–36]
  90
[70–100]
142
[94–177]
 
Diehl [32] 22   33
[28.5–35]
16.5
[16–18]
27
[25–28]
9.5
[9–11.75]
39.5
[33–45]
  45
[40–58]
198
[167–298]
55
[44–62]
Pedersen [38] 17 5.6
(1)
       62
(20)
  44.2
(8.2)
Roesthuis [33] 14     24
(3)
11
(2)
42
(3)
  57
(15)
162
(48)
57
(13)
Carsetti [39] 10    14
(1,49)
24
(2)
9.5
(3)
49
(9)
  70
(0.18)
119
(33.6)
 
Liu X [40] 8 7.5
(0.6)
20.1
(1.5)
9.6
(1.2)
23.6
(3)
14
(2.5)
33.9
(7.6)
   102
(27.9)
41.8
(3.7)
LUNG SAFE [50] 2377 7.6
[7.5–7.7]
20.8
[21.2–21.5]
8.4
[8.3–8.6]
23.2
[23, 24]
  32
[25–43]
  0.65
[0.64–0.65]
161
[158–163]
46
[45.4–46.6]
  1. Data are number, median [IQR], or mean (SD). PEEP, positive end expiratory pressure; Crs, compliance of the respiratory system; FiO2, fraction of inspired oxygen; PaO2 partial pressure of arterial oxygen; PaCO2 partial pressure of arterial carbon dioxide