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Table 3 Indices of preload responsiveness at different study times in preload responders and non-responders

From: Do changes in pulse pressure variation and inferior vena cava distensibility during passive leg raising and tidal volume challenge detect preload responsiveness in case of low tidal volume ventilation?

   Effects of PLR
(Vt = 6 mL/kg)
Effects of the Vt challenge
(Vt = 8 mL/kg)
Effects of VE
(Vt = 6 mL/kg)
ΔCI (% change)
Preload responders
Preload non-responders
18 ± 6
4 ± 4
− 9 ± 8
2 ± 6
25 ± 9
P preload non-responders versus preload responders < 0.01 < 0.01  
ΔVTI (% change)
Preload responders
Preload non-responders
16 ± 3
1 ± 1
− 10 ± 7
1 ± 7
 + 16 ± 8
P preload non-responders versus preload responders < 0.01 < 0.01  
ΔPPV (% change)
Preload responders
Preload non-responders
− 38 ± 16
− 4 ± 8
64 ± 42
1 ± 28
− 50 ± 12
P preload non-responders versus preload responders < 0.01 < 0.01  
ΔPPV (absolute change)
Preload responders
Preload non-responders
− 3 ± 1
0 ± 1
5 ± 2
0 ± 1
− 4 ± 2
P preload non-responders versus preload responders < 0.01 < 0.01  
ΔSVV (% change)
Preload responders
Preload non-responders
− 24 ± 20
1 ± 15
44 ± 22
− 1 ± 3
− 40 ± 17
P preload non-responders versus preload responders < 0.01 < 0.01  
ΔSVV (absolute change)
Preload responders
Preload non-responders
− 2 ± 2
0 ± 1
3 ± 2
− 1 ± 3
− 4 ± 2
P preload non-responders versus preload responders < 0.01 < 0.01  
ΔIVCDV (% change)
Preload responders
Preload non-responders
− 26 ± 28
− 3 ± 20
91 ± 72
− 10 ± 52
− 25 ± 15
P preload non-responders versus preload responders 0.02 < 0.01  
ΔIVCDV (absolute change)
Preload responders
Preload non-responders
− 2 ± 3
− 1 ± 2
6 ± 4
− 1 ± 4
− 2 ± 4
P preload non-responders versus preload responders 0.51 < 0.01  
  1. P values in bold: < 0.05
  2. ΔCI percent changes in cardiac index, ΔIVCDV percent changes in the inferior vena cava diameter variation, ΔPPV percent changes in pulse pressure variation, ΔSVV percent changes in stroke volume variation, ΔVTI percent changes in velocity time integral