Table 1 Baseline characteristics
Characteristics | No. (%) | ||
|---|---|---|---|
All | Women | Men | |
No. (%) | 2354 | 632 (26.8) | 1722 (73.2) |
Age, median (IQR), y | 61 (52–69) | 60 (50–70) | 61(53–69) |
Age, interval, y | |||
< 40 | 190 (8.1) | 77 (12.2) | 113 (6.6) |
40–49 | 266 (11.3) | 77 (12.2) | 189 (11.0) |
50–59 | 610 (25.9) | 149 (23.6) | 461 (26.8) |
60–69 | 724 (30.8) | 162 (25.6) | 562 (32.6) |
70–79 | 464 (19.7) | 133 (21.0) | 331 (19.2) |
≥ 80 | 100 (4.2) | 34 (5.4) | 66 (3.8) |
Admission month | |||
March | 394 (16.7) | 93 (14.7) | 301 (17.5) |
April | 1064 (45.2) | 270 (42.7) | 794 (46.1) |
May | 557 (23.7) | 162 (25.6) | 395 (22.9) |
June | 339 (14.4) | 107 (16.9) | 232 (13.5) |
Location before ICU admission | |||
Emergency department | 537 (22.8) | 123 (19.5) | 414 (24.0) |
Hospital floor | 1815 (77.1) | 508 (80.4) | 1307 (75.9) |
Time from symptom to ICU admission, median (IQR), d | 10 (7–13) | 9 (7–12) | 10 (7–13) |
Hospital level | |||
Tertiary | 911 (38.7) | 227 (35.9) | 684 (39.7) |
County | 1158 (49.2) | 311 (49.2) | 847 (49.2) |
Local | 285 (12.1) | 94 (14.9) | 191 (11.1) |
Days at hospital before ICU admission, d | |||
No. with data | 2338 | 625 | 1713 |
Median (IQR) | 1 (0–3) | 2 (0–4) | 1 (0–3) |
Pregnancy | 20 (3.2) | ||
Comorbidities | |||
None | 851 (36.2) | 216 (34.2) | 635 (36.9) |
One or more | 1503 (63.8) | 416 (65.8) | 1087 (63.1) |
Chronic hypertension | 955 (40.6) | 252 (39.9) | 703 (40.8) |
Chronic cardiac disease | 286 (12.1) | 47 (7.4) | 239 (13.0) |
COPD/Asthma | 343 (14.6) | 127 (20.1) | 216 (12.5) |
Immune deficiency | 144 (6.1) | 57 (9.0) | 87 (5.1) |
Chronic liver disease | 19 (0.8) | 8 (1.3) | 11 (0.6) |
Chronic kidney disease | 113 (4.8) | 25 (4.0) | 88 (5.1) |
Diabetes | 574 (24.4) | 143 (22.6) | 431 (25.0) |
Neuromuscular disease | 34 (1.4) | 10 (1.6) | 24 (1.4) |
Morbid obesitya | 165 (7.0) | 65 (10.3) | 100 (5.8) |
Malignancyb, No./total (%) | 44/2338 (1.9) | 14/625 (2.2) | 30/1713 (1.8) |
Vasopressor on admission, No./total (%) | 96/2338 (4.1) | 21/625 (3.4) | 75/1713 (4.4) |
Feverc, No./total (%) | 977/2190 (44.6) | 244/580 (42.1) | 733/1600 (45.8) |
Glasgow coma scale | |||
No. with data | 10,690 | 252 | 808 |
Median (IQR) | 15 (14–15) | 15 (14–15) | 15(14–15)[ |
Systolic blood pressure, mmHg | |||
No. with data | 2181 | 582 | 1599 |
Median (IQR) | 120 (100–140) | 116.5 (100–134) | 120 (103.5–140) |
Heart rate, beats/min | |||
No. with data | 2238 | 598 | 1640 |
Median (IQR) | 95 (82–110) | 95 (83–110) | 95 (82–110) |
PaO2, mmHg | |||
No. with data | 2081 | 566 | 1515 |
Median (IQR) | 9 (7.7–10.7) | 9 (7.7–10.7) | 9 (7.7–10.7) |
FiO2, % | |||
No. with data | 1583 | 429 | 1154 |
Median (IQR) | 70 (60–85) | 70 (60–89) | 70 (58.5–85) |
PaO2/FiO2 ratio | |||
No. with data | 1565 | 425 | 1140 |
Median (IQR) | 13.1 (9.9–18.0) | 12.9 (9.9–17.6) | 13.2 (10.0–18.4) |
White blood cell count, × 109/L | |||
No. with data | 2134 | 570 | 1564 |
Median (IQR) | 8.1 (6.0–10.9) | 7.6 (5.7–10.9) | 8.2 (6.2–10.9) |
pH | |||
No. with data | 2233 | 600 | 1633 |
Median (IQR) | 7.45 (7.39–7.48) | 7.44 (7.38–7.48) | 7.45 (7.40–7.48) |
Creatinine, mg/dL | |||
No. with data | 2143 | 571 | 1572 |
Median (IQR) | 0.8 (0.65–1.03) | 0.63 (0.51–0.83) | 0.85 (0.71–1.09) |
Bilirubin, mg/dL | |||
No. with data | 2057 | 546 | 1511 |
Median (IQR) | 0.53 (0.35–0.7) | 0.41 (0.29–0.58) | 0.53 (0.41–0.76) |
SAPS 3 at admission, median (IQR) | |||
No. with data | 2338 | 625 | 1713 |
Median (IQR) | 53 (47–60) | 54 (48–60) | 53 (46–60) |
Predicted risk of death, median (IQR), % | 0.22 (0.13–0.36) | 0.24 (0.14–0.36) | 0.22 (0.12–0.36) |
30-day mortality | 548 (23.3) | 135 (21.4) | 413 (24.0) |
90-day mortality | 634 (26.9) | 148 (23.4) | 486 (28.2) |