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Table 4 Safety outcomes

From: Diuretics decrease fluid balance in patients on invasive mechanical ventilation: the randomized-controlled single blind, IRIHS study

 

Control group N = 89

Intervention group N = 82

p value

KDIGO (N)

KDIGO 0

1 (1.1%)

0

0.9

KDIGO 1

51 (58.6%)

53 (69.7%)

0.2

KDIGO 2

6 (6.9%)

4 (5.3%)

0.7

KDIGO 3

29 (33.3%)

19 (25.0%)

0.3

Worsening of AKI

67 (75.3%)

46 (59.7%)

0.03

Natremia ≤ 135 mmol/L (N)

42 (47.2%)

33 (42.9%)

0.7

Natremia ≥ 145 mmol/L (N)

40 (44.9%)

40 (52%)

0.5

Episode of hypokalemia (N)

51 (57.3%)

53 (68.8%)

0.1

Duration of hypokalemia (d)

1 [0–2]

1 [0–4]

0.2

Cardiac rhythm troubles (N)

Atrial fibrillation

14 (15.3%)

9 (11.7%)

0.5

Torsade de pointes

0

1 (1.3%)

0.5

Ventricular tachycardia

2 (2.3%)

2 (2.6%)

0.9

Ventricular fibrillation

2 (2.3%)

1 (2.6%)

0.9

  1. Hypokalemia (≤ 3.5 mmol L−1)
  2. RRT renal replacement therapy