Variable | TBI cohort (matched samples) n = 90 | Control cohort n = 15 | TBI validation cohort (non-matched samples) n = 96 | Unit/metric |
---|---|---|---|---|
Age | 57 (41–62) | 25 (22–29) | 54 (36.5–63) | Years |
Male | 67 (74) | 7 (47) | 72 (75) | count (%) |
GCS admission | 7 (3–9) | 6 (3–11) | Scale 1–15 | |
GCS motor admission | 4 (1–5) | 4 (1–5) | Scale 1–6 | |
Pupils | Bilaterally responsive: 67 (74) | Bilaterally responsive: 69 (72) | Count (%) | |
Unilaterally unresponsive: 11 (12) | Unilaterally unresponsive: 9 (9.4) | |||
Bilaterally unresponsive: 9 (10) | Bilaterally unresponsive: 16 (17) | |||
Missing: 3 (3.3) | Missing: 2 (2.1) | |||
Head AIS | 1 (minor): 0 (0) | 1 (minor): 0 (0) | Score 1–6 | |
2 (moderate): 0 (0) | 2 (moderate): 1 (1.0) | |||
3 (serious): 10 (11) | 3 (serious): 10 (10.4) | |||
4 (severe): 30 (33) | 4 (severe): 25 (26) | |||
5 (critical): 43 (48) | 5 (critical): 57 (59) | |||
6 (maximum): 0 (0) | 6 (maximum): 0 (0) | |||
Missing: 7 (7.8) | Missing: 3 (3.1) | |||
ISS | 25 (19–29) | 25 (17–29) | Scale | |
Missing: 7 (7.78) | Missing: 3 (3.1) | |||
Multitrauma | 29 (32) | 26 (27) | Count (%) | |
Hypotension at SoA | 2 (2.2) | 1 (1.0) | Count (%) | |
Missing: 24 (27) | Missing: 26 (27) | |||
Hypoxia at SoA | 15 (17) | 18 (19) | Count (%) | |
Missing: 4 (4.4) | Missing: 4 (4.2) | |||
Stockholm CT score | 2.5 (2–3.3) | 2.5 (1.9–3.3) | Scale | |
QA | 0.0041 (0.0018–0.011) | 0.0040 (0.0035–0.0060) | 0.009 (0.003–0.027) | Quotient |
Missing: 19 (21.1) | Missing: 71 (74) | |||
APOE allele status | No allele: 57 (63) | No allele: 64 (67) | Count (%) | |
Heterozygote: 16 (18) | Heterozygote: 17 (18) | |||
Homozygote: 2 (2) | Homozygote: 3 (3.1) | |||
Missing: 15 (17) | Missing: 12 (12.5) | |||
Evacuation aSDH | 33 (38) | 50 (61) | ||
Evacuation EDH | 6 (6.8) | 14 (17) | ||
Evacuation tICH | 24 (27) | 13 (16) | ||
ICP monitora | 38 (43) | 60 (73) | ||
Other intracranial monitorationb | 55 (63) | 39 (48) | ||
GOS | GOS 1 (death): 12 (13) | GOS 1 (death): 10 (10.4) | Score 1–5 | |
GOS 2 (vegetative): 0 (0) | GOS 2 (vegetative): 1 (1.0) | |||
GOS 3 (severe disability): 34 (38) | GOS 3 (severe disability): 30 (31) | |||
GOS 4 (moderate disability): 28 (31) | GOS 4 (moderate disability): 29 (30) | |||
GOS 5 (good recovery): 16 (18) | GOS 5 (good recovery): 26 (27) | |||
Unfavorable GOS | GOS 1–3: 46 (51) | GOS 1–2: 41 (43) | count (%) |