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Table 4 Multivariate analysis of factors associated with helmet CPAP failure

From: Helmet CPAP to treat hypoxic pneumonia outside the ICU: an observational study during the COVID-19 outbreak

Factora

P value

Odds ratio [95% C.I.]

C-reactive protein, mg/L

0.001

1.006 [1.003–1.010]

Hospital admission to oxygen therapy failure, days

0.001

0.775 [0.661–0.908]

Age, years

0.002

1.054 [1.020–1.089]

PaO2/FiO2 ratio (helmet CPAP), mmHg

0.003

0.995 [0.991–0.998]

Comorbidities, n

0.005

1.582 [1.147–2.182]

  1. CPAP: continuous positive airway pressure
  2. afactors entered in the backward regression model and removed due to lack of statistical significance (P > 0.05): sex, body temperature, PaO2/FiO2 ratio and PaCO2 during standard oxygen treatment, PaCO2 measured during CPAP. C-reactive protein, time to oxygen mask failure, age, PaO2/FiO2 ratio collected during helmet CPAP treatment and number of comorbidities were independently associated with helmet CPAP failure.
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Critical Care

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