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Table 3 Comparison of markers of endothelial and epithelial dysfunction between patients with COVID-19-related ARDS and classical ARDS

From: Markers of endothelial and epithelial pulmonary injury in mechanically ventilated COVID-19 ICU patients

Biomarker Covid-19-related ARDS
(n = 31)
Classical ARDS
(n = 11)
p value
RAGE, pg/mL 60 [18–274] 789 [440–1021]  < 0.001
ICAM-1, ng/mL 1093 [575–1515] 75.7 [63.1–89.6]  < 0.001
VCAM-1, ng/mL 1114 [804–1708] 739 [439–1021] 0.019
Ang-2, pg-mL 3909 [1658–6348] 1045 [627–1654]  < 0.001
P-selectin, ng/mL 93 [50–145] 750 [631–1103]  < 0.001
E-selectin, ng/mL 24.9 [19.2–42.5] 3.3 [2.4–5.7]  < 0.001
  1. Data are reported as median [interquartile range]
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