Table 3 Comparison of markers of endothelial and epithelial dysfunction between patients with COVID-19-related ARDS and classical ARDS
Biomarker | Covid-19-related ARDS (n = 31) | Classical ARDS (n = 11) | p value |
|---|---|---|---|
RAGE, pg/mL | 60 [18–274] | 789 [440–1021] | < 0.001 |
ICAM-1, ng/mL | 1093 [575–1515] | 75.7 [63.1–89.6] | < 0.001 |
VCAM-1, ng/mL | 1114 [804–1708] | 739 [439–1021] | 0.019 |
Ang-2, pg-mL | 3909 [1658–6348] | 1045 [627–1654] | < 0.001 |
P-selectin, ng/mL | 93 [50–145] | 750 [631–1103] | < 0.001 |
E-selectin, ng/mL | 24.9 [19.2–42.5] | 3.3 [2.4–5.7] | < 0.001 |