|
Parameter
|
cfDNA
|
MPO-DNA
|
C3
|
C5
|
|---|
|
R
|
P
|
R
|
P
|
R
|
P
|
R
|
P
|
|---|
|
Immunological parametersa
|
|
WBC (× 109/L)
|
0.367
|
< 0.001
|
0.183
|
0.036
|
0.190
|
0.037
|
0.102
|
0.265
|
|
Neutrophil (× 109/L)
|
0.439
|
< 0.001
|
0.305
|
0.001
|
0.318
|
0.001
|
0.129
|
0.159
|
|
CRP (U/L)
|
0.374
|
< 0.001
|
0.065
|
0.515
|
0.194
|
0.040
|
0.205
|
0.029
|
|
Coagulation parametersb
|
|
D-dimer (g/L)
|
0.347
|
0.007
|
0.2442
|
0.043
|
0.240
|
0.024
|
0.139
|
0.196
|
|
PT (s)
|
0.615
|
< 0.001
|
0.073
|
0.484
|
− 0.0043
|
0.686
|
0.139
|
0.190
|
|
FDP (μg/mL)
|
0.474
|
< 0.001
|
0.316
|
0.002
|
0.300
|
0.005
|
0.068
|
0.526
|
|
PTA (%)
|
− 0.585
|
< 0.001
|
− 0.0725
|
0.4851
|
0.041
|
0.704
|
− 0.148
|
0.164
|
|
INR
|
0.588
|
< 0.001
|
0.073
|
0.480
|
− 0.042
|
0.695
|
0.144
|
-.175
|
|
Tissue damage parametersa
|
|
LDH (U/L)
|
0.379
|
< 0.001
|
0.306
|
0.003
|
0.162
|
0.100
|
0.143
|
0.149
|
|
DBIL (µmol/L)
|
0.496
|
< 0.001
|
0.009
|
0.367
|
0.303
|
0.004
|
− 0.034
|
0.755
|
|
TBIL (µmol/L)
|
0.360
|
< 0.001
|
0.054
|
0.599
|
0.304
|
0.005
|
− 0.072
|
0.507
|
|
CK(U/L)
|
0.309
|
< 0.001
|
0.308
|
0.004
|
0.074
|
0.506
|
− 0.104
|
0.349
|
|
GFR (g/L)
|
− 0.389
|
< 0.001
|
− 0.187
|
0.165
|
− 0.333
|
0.002
|
− 0.129
|
0.236
|
- Correlations were calculated by Spearman correlation analysis (r). a, the immunological parameters and tissue damage parameters were analyzed in all enrolled patients (n = 135); b, coagulation parameters were measured in 60 patients according to the needs of clinical examination. Mild, n = 19; Severe, n = 41. Abbreviations: WBC, white blood cells; CRP, C-reactive protein; PT, thrombin time; FDP, fibrin(-ogen) degradation products; PTA, prothrombin activity; INR, international normalized ratio; LDH, lactate dehydrogenase; DBIL, direct bilirubin; TBIL, total bilirubin; CK, creatine kinase; GFR, glomerular filtration rate
- P < 0.05 was considered statistically significant and is shown in bold
