Table 6 HRIM analysis before and after metoclopramide administration in critically ill patients

GRV during the study (mL)

30 (18–90)

15 (0–20)

90 (88–200)

15 (10–160)

10 (0–10)

160 (88–213)

Number of esophageal activities /hour

10 (6–17)

17 (11–26)

6 (4–8)

7 (5–13)*

11 (7–15)*

5 (4–9)

Distal contractile integral (mmHg cm s)

3852 (1700–7730)

7661 (1580–11,908)

3111 (1700–5068)

3004 (1900–8091)

5096 (1699–8916)

2805 (2081–4488)

Failed esophageal peristalsis (median of %)

73 (54–89)

62 (50–73)

85 (69–98)

80 (58–100)

68 (53–85)

94 (69–100)

Panesophageal pressurization (median of %)

64 (48–79)

62 (50–73)

69 (43–83)

74 (45–88)

68 (53–85)

80 (45–90)

Double-peaked waves (median of %)

30 (0–50)

48 (43–51)

0 (0–5)

0 (0–25)**

25 (8–35)*

0 (0–0)

Premature contraction (median of %)

20 (2–32)

31 (25–37)

2 (1–19)

10 (0–41)

33 (10–48)

0 (0–3)

Integrated relaxation pressure (mmHg)

16 (6–21)

20 (16–28)

6 (6–16)

14 (7–19)

17 (14–24)*

7 (6–10)

Intrabolus pressure (mmHg)

23 (17–28)

19 (16–27)

25 (19–30)

24 (20–27)

24 (21–26)

24 (19–29)

LES tone (mmHg)

18 (9–26)

25 (19–31)

9 (8–16)

18 (12–27)

23 (18–30)

12 (9–20)

EGJ-CI (mmHg cm)

40 (28–60)

53 (40–60)

30 (20–50)

33 (2–53)

43 (30–53)*

30 (26–44)

Inspiration EGJ pressure (mmHg)

36 (29–42)

40 (35–48)

34 (28–36)

42 (30–44)

40 (34–45)

42 (27–44)*

Expiration EGJ pressure (mmHg)

24 (19–33)

30 (22–35)

20 (19–25)

25 (23–32)

27 (24–32)

23 (21–29)*

Number of reflux episodes/patient/hour

1.8 (0.5–3.5)

3.3 (2–3.6)

0.8 (0.4–1.5)

2.4 (0.9–3.6)

2.9 (2.3–3.7)

1.1 (0.5–2.6)