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Table 2 Quantitative CT analysis parameters

From: Computed tomography assessment of PEEP-induced alveolar recruitment in patients with severe COVID-19 pneumonia

Parameter All (N = 42) Non-recruiters (N=32) Recruiters (N=10)
PEEP 8 cmH2O PEEP 16 cmH2O p PEEP 8 cmH2O PEEP 16 cmH2O p PEEP 8 cmH2O PEEP 16 cmH2O p
Total lung volume (ml) 3076 [2610–3810] 3461 [2982–4190] <0.001* 3120 [2687–3727] 3575 [3107–4150] <0.001* 2619 [2331–3907] 2953 [2454–4645] 0.005*
Total lung weight (g) 1515 [1295–1811] 1539 [1336–1852] 0.866 1504 [1274–2091] 1520 [1322–2126] 0.080 1532 [1302–1773] 1455 [1244–1728] 0.116
Excess lung weight (%) 56.6 [24.0–74.8]    56.7 [23.2–90.5]    55.0 [26.3–59.59]   
Gas volume (ml) 1360 [1064–2118] 1858 [1301–2599] <0.001* 1448 [1105–2159] 1931 [1459–2583] <0.001* 1216 [701–2115] 1540 [1085–2957] 0.005*
Mean attenuation (HU) -526 [-591–-329] -565 [-637–-404] <0.001* -549 [-616–-333] -581 [-644–-405] <0.001* -434 [-541–-301] -539 [-634–-379] 0.005*
Hyper-aerated mass (g) 14 [7–28] 23 [12–39] <0.001* 17 [8–29] 26 [13–39] <0.001* 12 [5–17] 17 [8–43] 0.005*
Normally aerated mass (g) 367 [259–465] 424 [347–528] <0.001* 375 [307–462] 440 [366–532] <0.001* 331 [190.9–504.4] 383 [267.4–520.3] 0.005*
Poorly aerated mass (g) 504 [391–671] 487 [346–673] <0.001* 504 [388–687] 496 [349–683] 0.001* 477 [393.9–587.5] 433 [328.1–580.8] 0.093
Non aerated mass (g) 625 [377–810] 576 [354–775] <0.001* 564 [375–785] 581 [350–854] 0.014* 737 [515.7–819.1] 573 [435.2–710.4] 0.005*
Dynamic lung strain 0.33 [0.23–0.46] 0.26 [0.19–0.35] <0.001* 0.33 [0.24–0.43] 0.25 [0.19–0.3] <0.001* 0.41 [0.22–0.63] 0.33 [0.16–0.45] <0.005*
  1. Data are presented as median [interquartile range]
  2. PEEP positive end-expiratory pressure, HU Hounsfield Units, IQR interquartile range, CI confidence interval
  3. *Signigicant difference between PEEP levels, p < 0.05