From: The role of pro-opiomelanocortin in the ACTH–cortisol dissociation of sepsis
Human study 1 | P value | Human study 2 | P value | |||
---|---|---|---|---|---|---|
Patients n = 51 | Controls n = 20 | Patients n = 47 | Controls n = 20 | |||
Gender—male, n (%) | 33 (68%) | 11 (55%) | .45 | 37 (79%) | 14 (70%) | .44 |
Age—y, mean (SD) | 60.0 ± 5.1 | 58.5 ± 15.8 | .55 | 63.3 ± 13.7 | 64.1 ± 10.9 | .80 |
BMIa—kg/m2, mean (SD) | 26.1 ± 4.6 | 24.3 ± 3.0 | .06 | 27.5 ± 5.8 | 26.6 ± 3.0 | .40 |
Diabetes mellitus, n (%) | 8 (16%) | 8 (17%) | ||||
Malignancy, n (%) | 14 (27%) | 9 (19%) | ||||
APACHE II scoreb, mean (SD) | 30.3 ± 8.2 | 32.0 ± 7.4 | ||||
Urgent admission, n (%) | 44 (86%) | 41 (87%) | ||||
Sepsisc, n (%) | 51 (100%) | 47 (100%) | ||||
Septic shockc, n (%) | 13 (25%) | 38 (81%) |