Fig. 1From: Angiopoietin-2 outperforms other endothelial biomarkers associated with severe acute kidney injury in patients with severe sepsis and respiratory failurea Hospital mortality rates of severe septic patients were significantly associated with severity of AKI. b Serum creatinine levels were significantly higher in sepsis with AKI compared to patients without AKI within the four study days. c Sepsis patients with AKI stage 1 on enrollment day had a higher proportion of recovery from AKI at 48 or 72 h after enrollment, while a higher percentage of sepsis patients with AKI stage 3 on enrollment day remained in the severe AKI status at 48 or 72 h after enrollment. Groups in panel a were analyzed by linear-by linear association test. Data in panel b were summarized as boxplots where box encompassed 25‒75th percentile, error bars encompassed 10‒90th percentile and horizontal line showed median. Groups in panel b were compared by Mann–Whitney U testBack to article page