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Fig. 4 | Critical Care

Fig. 4

From: Monitoring circulating dipeptidyl peptidase 3 (DPP3) predicts improvement of organ failure and survival in sepsis: a prospective observational multinational study

Fig. 4

Association between the changes of circulating DPP3 (cDPP3) levels over 24 h and mortality (A) Association between cDPP3 and 28-day mortality in time-dependent Cox regression, and worsening of SOFA score within 48 h in patients alive at 48 h (C) HR between high-high (HH) (levels of cDPP3 remained high) and high-low (HL) (levels of cDPP3 declining over 24 h) 0.18 (95% CI 0.08–0.41). HR between low-low (LL) (levels of cDPP3 remaining low) and low–high (LH) (levels of cDPP3 increasing over 24 h) 2.2 [1.0–4.8], p = 0.0015). For patients discharged prior to 48 h, the 48 h SOFA was set to 0

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Critical Care

ISSN: 1364-8535