Death in hospital following ICU discharge: insights from the LUNG SAFE study

Table 6 Factors associated with hospital mortality in patients with no treatment limitations at ICU discharge

	OR (95% CI)	p value
Multivariable logistic regression model 1 (n = 1438 on 2328)
Age (years)	1.044 (1.028–1.061)	< .0001
Adjusted SOFA score at last available day in ICU	1.154 (1.090–1.222)	< .0001
Immune-incompetence (ref. No)	2.086 (1.281–3.397)	0.0031
Adjunctive measures during ICU stay (ref. No)	0.574 (0.340–0.970)	0.0383
Multivariable logistic regression model on patients on MV for at least 2 days (from AHRF onset) (n = 1043 on 1656)
Age (years)	1.048 (1.029–1.067)	< .0001
Adjusted SOFA score at last available day in ICU	1.167 (1.091–1.248)	< .0001
Immune-incompetence (ref. No)	1.938 (1.071–3.509)	0.0288
BMI (kg/m²)	0.954 (0.911–0.999)	0.0469

Model 1 was identified by stepwise approach using as possible predictors: baseline patients’ characteristics, parameters of illness of severity at last available day in ICU, use of adjunctive measures during ICU stay and ICU characteristics.
Model 2 was identified by stepwise approach using as possible predictors: baseline patients’ characteristics, parameters of illness of severity and ventilator setting at last available day in ICU, use of adjunctive measures during ICU stayand ICU characteristics
CI confidence interval, ICU intensive care unit, OR odds ratio, SOFA sequential organ failure assessment

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