Table 3 Ventilator setting in patients with no treatment limitations at ICU discharge who received invasive MV for at least 2 days (from AHRF onset) stratified by vital status at hospital discharge
From: Death in hospital following ICU discharge: insights from the LUNG SAFE study
Parameter | Alive N = 2186 | Dead N = 142 | Total N = 2328 | p value |
|---|---|---|---|---|
Patients on IMV at 1st and 2nd day, n (%) | 1545 (70.68) | 111 (78.17) | 1656 (71.13) | 0.0562 |
Last day on IMV (with collected data), median [IQR] | 7 [3–20] | 7 [3–10] | 7 [3–10] | 0.7307 |
Non-invasive Mechanical Ventilation after IMV, n (%) | 144 (9.32) | 7 (6.31) | 151 (9.12) | 0.2866 |
Ventilator setting at 1st day of Invasive MV | ||||
Controlled ventilation, n (%) | 1081 (71.21) | 76 (69.72) | 1157 (7111) | 0.7407 |
FiO2, median [IQR] | 0.60 [0.40–0.80] | 0.50 [0.40–0.70] | 0.57 [0.40–0.80] | 0.1899 |
Set respiratory rate (breaths/min), mean ± SD | 17.92 ± 5.83 | 17.66 ± 5.38 | 17.90 ± 5.80 | 0.7580 |
Total respiratory rate (breaths/min), mean ± SD | 19.74 ± 6.14 | 19.51 ± 5.84 | 19.73 ± 6.12 | 0.7573 |
Tidal volume (ml/kg IBW), mean ± SD | 7.77 ± 1.83 | 7.78 ± 1.88 | 7.77 ± 1.84 | 0.6565 |
High tidal volume (> 8 ml/kg IBW), n (%) | 543 (36.86) | 42 (40.00) | 585 (37.07) | 0.5203 |
Dynamic compliance (ml/cmH2O), mean ± SD | 33.35 ± 23.96 | 32.23 ± 23.04 | 33.27 ± 23.89 | 0.2753 |
PEEP (cmH2O), mean ± SD | 8.12 ± 3.21 | 7.40 ± 2.85 | 8.07 ± 3.19 | 0.0095 |
PIP (cmH2O), mean ± SD | 26.04 ± 7.99 | 25.50 ± 8.02 | 26.01 ± 7.99 | 0.5395 |
Plateau pressure measured, n (%) | 489 (31.65) | 33 (29.73) | 522 (31.52) | 0.6740 |
Plateau pressure (cmH2O), mean ± SD | 21.50 ± 5.62 | 21.73 ± 6.27 | 21.52 ± 5.66 | 0.9205 |
Driving pressure (cmH2O), mean ± SD | 13.19 ± 5.03 | 14.64 ± 5.81 | 13.28 ± 5.09 | 0.1699 |
Minute ventilation (l/min), mean ± SD | 9.32 ± 2.87 | 9.06 ± 3.07 | 9.30 ± 2.89 | 0.1545 |
Standardized minute ventilation (l/min), mean ± SD | 10.43 ± 4.45 | 9.96 ± 3.94 | 10.40 ± 4.42 | 0.4408 |
Ventilator setting at last available day of Invasive MV in ICU | ||||
Controlled ventilation, n (%) | 384 (25.35) | 25 (23.15) | 409 (25.20) | 0.6112 |
FiO2 | ||||
Median [IQR] | 0.40 [0.35–0.45] | 0.40 [0.30–0.40] | 0.40 [0.35–0.45] | 0.0309 |
Available data, n (%) | 1501 (97.15) | 107 (96.40) | 1608 (97.10) | 0.5586 |
Total respiratory rate (breaths/min) | ||||
Mean ± SD | 20.21 ± 12.15 | 20.91 ± 6.76 | 20.26 ± 11.86 | 0.1920 |
Available data, n (%) | 1499 (97.02) | 109 (98.20) | 1608 (97.10) | 0.7674 |
Tidal volume (ml/kg IBW) | ||||
High tidal volume (> 8 ml/kg IBW), n (%) | 602 (42.82) | 42 (42.00) | 644 (42.76) | 0.8733 |
Mean ± SD | 7.95 ± 2.06 | 7.89 ± 2.04 | 7.95 ± 2.06 | 0.9763 |
Available data, n (%) | 1406 (91.00) | 100 (90.09) | 1506 (90.94) | 0.7461 |
Dynamic compliance (ml/cmH2O) | ||||
Mean ± SD | 49.39 ± 45.70 | 48.72 ± 30.39 | 49.35 ± 44.84 | 0.1701 |
Available data, n (%) | 1344 (86.99) | 96 (86.49) | 1440 (86.96) | 0.8790 |
PEEP (cmH2O) | ||||
Mean ± SD | 6.66 ± 2.43 | 6.26 ± 1.95 | 6.63 ± 2.40 | 0.0597 |
Available data, n (%) | 1496 (96.83) | 106 (95.50) | 1602 (96.74) | 0.4043 |
PIP (cmH2O) | ||||
Mean ± SD | 20.17 ± 7.16 | 18.51 ± 7.01 | 20.06 ± 7.16 | 0.0079 |
Available data, n (%) | 1395 (90.29) | 99 (89.19) | 1494 (90.22) | 0.7058 |
Minute ventilation (l/min) | ||||
Mean ± SD | 9.65 ± 4.08 | 9.56 ± 3.25 | 9.64 ± 4.03 | 0.9026 |
Available data, n (%) | 1447 (93.66) | 103 (92.79) | 1550 (93.60) | 0.7194 |
Standardized minute ventilation (l/min) | ||||
Mean ± SD | 10.11 ± 4.93 | 10.04 ± 4.00 | 10.10 ± 4.87 | 0.7355 |
Available data, n (%) | 1257 (81.36) | 92 (82.88) | 1349 (81.46) | 0.6899 |