Factor | CPC All | Good neurological outcome, CPC 1–2 | Poor neurological outcome, CPC 3–5 | p value |
---|---|---|---|---|
N, n (%) | 164 (100%) | 66 (40%) | 98 (60%) | Â |
Sociodemographics | ||||
Age, mean (SD) | 63 (15) | 60 (17) | 65 (14) | 0.027 |
Male, n (%) | 117 (71.3%) | 55 (83%) | 62 (63%) | 0.008 |
Comorbidities | ||||
Coronary heart disease, n (%) | 109 (66.5%) | 50 (76%) | 59 (60%) | 0.044 |
Congestive heart failure, n (%) | 20 (12.2%) | 7 (11%) | 13 (13%) | 0.81 |
COPD, n (%) | 15 (9.1%) | 3 (5%) | 12 (12%) | 0.11 |
Liver disease, n (%) | 3 (1.8%) | 0 (0%) | 3 (3%) | 0.27 |
Hypertension, n (%) | 86 (52.4%) | 37 (56%) | 49 (50%) | 0.52 |
Diabetes, n (%) | 39 (23.8%) | 9 (14%) | 30 (31%) | 0.015 |
Chronic kidney disease, n (%) | 24 (14.6%) | 8 (12%) | 16 (16%) | 0.51 |
Malignant disease, n (%) | 14 (8.5%) | 2 (3%) | 12 (12%) | 0.047 |
Neurological disease, n (%) | 13 (7.9%) | 2 (3%) | 11 (11%) | 0.077 |
Resuscitation measures | ||||
No-flow time, min, mean (SD) | 4.22 (5.93) | 1.70 (2.96) | 6.02 (6.83) |  < 0.001 |
Low-flow time, min, mean (SD) | 20.42 (15.13) | 16.53 (14.30) | 23.12 (15.17) | 0.006 |
Cardiac arrest setting | ||||
At home | 63 (38.4%) | 16 (24%) | 47 (48%) |  < 0.001 |
In public | 78 (47.6%) | 43 (65%) | 35 (36%) | |
In hospital | 23 (14.0%) | 7 (11%) | 16 (16%) | |
Witnessed | 137 (83.5%) | 63 (95%) | 74 (76%) |  < 0.001 |
Bystander CPR | 103 (62.8%) | 51 (77%) | 52 (53%) | 0.002 |
Initial heart rhythm | ||||
Ventricular tachycardia | 6 (3.7%) | 2 (3%) | 4 (4%) |  < 0.001 |
Ventricular fibrillation | 88 (53.7%) | 53 (80%) | 35 (36%) | |
Asystole | 35 (21.3%) | 2 (3%) | 33 (34%) | |
Pulseless electrical activity | 29 (17.7%) | 6 (9%) | 23 (23%) | |
Unknown | 6 (3.7%) | 3 (5%) | 3 (3%) | |
Epinephrine during resuscitation (mg), mean (SD) | 2.18 (2.55) | 1.08 (1.76) | 2.96 (2.73) |  < 0.001 |
Targeted temperature management (TTM), n (%) | 109 (66.5%) | 40 (61%) | 69 (70%) | 0.19 |
Initial clinical parameter and levels of routine blood markers | ||||
GCS, mean (SD) | 7.3 (4.1) | 7 (5) | 4 (1) |  < 0.001 |
pH, mean (SD) | 7.25 (0.12) | 7.29 (0.09) | 7.22 (0.13) | 0.003 |
Lactate, mean (SD) | 7.3 (4.1) | 5.9 (3.3) | 8.3 (4.2) |  < 0.001 |
NfL (pg/ml), mean (SD) | 429 (1415) | 49 (111) | 685 (1787) | 0.004 |
NfL (pg/ml), median (IQR) | 51 (21, 173) | 27 (13, 46) | 116 (41, 330) |  < 0.001 |