Monocytic HLA-DR expression kinetics in septic shock patients with different pathogens, sites of infection and adverse outcomes

Table 2 Cox proportional hazard analysis for secondary infections, mortality and adverse outcome

		Hazard ratio [95% CI] (unadjusted)	p value	Hazard ratio [95% CI] adjusted for baseline SOFA score	p value
Secondary infections	Decliners vs. early improvers	2.0 [0.6–7.2]	0.27	2.5 [0.6–9.4]	0.19
Secondary infections	Delayed or non-improvers vs. early improvers	1.6 [0.6–4.3]	0.37	1.5 [0.5–4.0]	0.45
Mortality	Decliners vs. early improvers	3.3 [1.2–9.2]	0.02	2.5 [0.8–7.8]	0.10
Mortality	Delayed or non-improvers vs. early improvers	1.7 [0.7–4.1]	0.20	1.7 [0.7–4.0]	0.26
Adverse outcome (secondary infection or death)	Decliners vs. early improvers	2.9 [1.2–6.9]	0.02	2.8 [1.1–7.1]	0.03
Adverse outcome (secondary infection or death)	Delayed or non-improvers vs. early improvers	2.1 [1.0–4.1]	0.04	2.0 [1.0–4.0]	0.057

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