Table 1 Patient characteristics according to the status of renal replacement therapy in patients who developed stage 3 acute kidney injury after out-of-hospital cardiac arrest
Total (n = 223) | Non-RRT group (n = 108) | RRT group (n = 115) | P value | |
|---|---|---|---|---|
Baseline characteristics | ||||
Age, years | 61 (49–73) | 64 (52–73) | 61 (49–73) | 0.39 |
Male gender | 156 (70.3) | 71 (65.7) | 85 (74.6) | 0.15 |
Body weight, kg | 69 (60–75) | 65 (59–73) | 69 (60–75) | 0.16 |
Past medical history | ||||
Hypertension | 104 (46.6) | 55 (50.9) | 49 (42.6) | 0.21 |
Heart failure | 10 (4.5) | 4 (3.7) | 6 (5.2) | 0.75 |
Diabetes mellitus | 65 (29.1) | 35 (32.4) | 30 (26.1) | 0.30 |
Cardiac arrest | ||||
Arrest location | 0.09 | |||
Home | 126 (56.5) | 67 (62.0) | 59 (51.3) | |
Workplace | 10 (4.5) | 4 (3.7) | 6 (5.2) | |
Street | 47 (21.1) | 19 (17.6) | 28 (24.3) | |
Public building | 30 (13.5) | 16 (14.8) | 14 (12.2) | |
Nursing home | 5 (2.2) | 1 (0.9) | 4 (3.5) | |
Unknown | 5 (2.2) | 1 (0.9) | 4 (3.5) | |
Witnessed arrest | 138 (62.7) | 62 (58.5) | 76 (66.7) | 0.21 |
Bystander CPR | 136 (62.1) | 64 (59.8) | 72 (64.3) | 0.50 |
Time from collapse to CPR, min | 1 (0–7) | 3 (0–8) | 1 (0–7) | 0.58 |
Time from CPR to ROSC, min | 40 (26–53) | 40 (29–50) | 40 (26–53) | 0.75 |
Epinephrine, mg | 2 (1–7) | 3 (1–5) | 2 (1–7) | 0.83 |
Initial rhythm | 0.04 | |||
Vf | 48 (21.5) | 12 (11.1) | 36 (31.3) | |
Pulseless VT | 1 (0.4) | 1 (0.9) | 0 (0.0) | |
PEA | 47 (21.1) | 24 (22.2) | 23 (20.0) | |
Asystole | 91 (40.8) | 55 (50.9) | 36 (31.3) | |
Unknown shockable | 4 (1.8) | 2 (1.9) | 2 (1.7) | |
Unknown non-shockable | 1 (0.4) | 0 (0.0) | 1 (0.9) | |
Unknown | 31 (13.9) | 14 (13.0) | 17 (14.8) | |
Arrest cause | < 0.001 | |||
Medical or unknown | 168 (75.3) | 68 (63.0) | 100 (87.0) | |
Trauma | 5 (2.2) | 3 (2.8) | 2 (1.7) | |
Submersion | 5 (2.2) | 4 (3.7) | 1 (0.9) | |
Drug overdose | 3 (1.3) | 1 (0.9) | 2 (1.7) | |
Asphyxia | 12 (5.4) | 10 (9.3) | 2 (1.7) | |
Hanging | 30 (13.5) | 22 (20.4) | 8 (7.0) | |
Post-resuscitation | ||||
Lactate after ROSC, mmol/L | 12.2 (8.9–14.8) | 11.4 (8.6–14.5) | 12.2 (8.9–14.8) | 0.36 |
Shock after ROSC | 210 (94.2) | 101 (93.5) | 109 (94.8) | 0.69 |
TT of 36 °C | 47 (21.1) | 18 (16.7) | 29 (25.2) | 0.12 |
TTM duration of 48 h | 5 (2.2) | 3 (2.8) | 2 (1.7) | 0.68 |
Adverse events during 7 days since ROSC | ||||
Seizure | 38 (17.0) | 17 (15.7) | 21 (18.3) | 0.62 |
Bleeding | 16 (7.2) | 3 (2.8) | 13 (11.3) | 0.02 |
Sepsis | 54 (24.2) | 24 (22.2) | 30 (26.1) | 0.50 |
Hypoglycaemia | 44 (19.7) | 18 (16.7) | 26 (22.6) | 0.27 |
Sustained hyperglycaemia | 153 (68.6) | 72 (66.7) | 81 (70.4) | 0.55 |
Tachycardia | 49 (22.1) | 24 (22.2) | 25 (21.9) | 0.96 |
Bradycardia | 6 (2.7) | 3 (2.8) | 3 (2.6) | 1.00 |
Re-arrest | 55 (24.8) | 22 (20.6) | 34 (28.7) | 0.16 |