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Table 1 Clinical demographics and baseline characteristics by initial fluid resuscitation rate (ml/kg/min)

From: Effect of initial infusion rates of fluid resuscitation on outcomes in patients with septic shock: a historical cohort study

VariablesFluid replacement rate; ml/kg/minP value
≥ 0. 5, N = 2560.25–0.49, N = 1230.17–0.24, N = 88< 0.17, N = 585
Age; year, median (IQR)66 (55, 78)68 (59, 80)70 (53, 79)67 (56, 77).5
Male sex; N (%)126 (49%)65 (53%)40 (46%)296 (51%).7
White race; N (%)242 (95%)114 (93%)79 (90%)526 (90%).2
Hospital admission weight; kg, median (IQR)76 (63, 90)81 (64, 100)80 (67, 103)84 (69, 99)< .001
Charlson comorbidity index; median (IQR)5 (3, 8)6 (4, 8)6 (3, 8)6 (4, 8).9
APACHE III score (T0); median (IQR)82 (64, 104)83 (69, 106)86.5 (73, 107)86 (70, 103).3
SOFA score (T0); median (IQR)8 (6, 11)9 (7, 12)9.0 (6.5, 11.0)9 (6, 12).4
Infection source
 Blood73 (29%)32 (26%)25 (28%)155 (26%).9
 Respiratory95 (37%)38 (31%)37 (43%)274 (47%).002
 Abdominal/GI44 (17%)13 (11%)10 (11%)78 (13%).2
 Urinary55 (21%)28 (23%)32 (37%)135 (23%).02
 Soft tissue and bone24 (9%)11 (9%)13 (15%)41 (7%).08
 Other23 (9%)13 (11%)12 (14%)54 (9%).5
Heart rate (T0), bpm; median (IQR)101 (88, 116)100 (83, 113)105 (88, 117)98 (83, 111).007
Mean arterial pressure (T0), mmHg; median (IQR)64 (57, 73)60 (54, 68)65 (57, 75)66 (59, 76)< .001
VIS (T0); median (IQR)1.6 (0.5, 10.1)1.5 (0.6, 12.8)1.7 (0.7, 7.2)1.7 (0.6, 10.6).9
  1. Numbers indicate N (%) unless otherwise noted
  2. Kruskal-Wallis
  3. Chi-square