Effect of an ICU diary on psychiatric disorders, quality of life, and sleep quality among adult cardiac surgical ICU survivors: a randomized controlled trial

Table 3 Comparison of outcomes between groups post-intervention

Variables	mITT				PP
Variables	Intervention (n = 46)	Control (n = 49)	T/Z	P	Intervention (n = 41)	Control (n = 42)	T/Z	P
Primary outcome
IES-R total score	20.54 ± 10.93	25.16 ± 11.98	− 1.96	0.052	20.73 ± 12.12	25.17 ± 12.97	− 1.61	0.11
Avoidance score	6.41 ± 4.66	7.80 ± 5.11	− 1.38	0.17	6.71 ± 5.24	7.83 ± 5.53	− 0.95	0.34
Intrusion	9.09 ± 5.32	10.53 ± 4.98	− 1.36	0.18	9.00 ± 5.59	10.48 ± 5.37	− 1.23	0.22
Hyperarousal	5.05 ± 3.52	6.84 ± 3.67	− 2.43	0.02*	5.02 ± 3.73	6.86 ± 3.97	− 2.17	0.03*
Secondary outcomes ICU memories
Factual memories	7.26 ± 2.52	5.93 ± 2.85	2.14	0.02*	7.26 ± 2.61^c	5.93 ± 3.09	2.14	0.04*
Feeling memories	2 (1.2)	2 (1.3)	− 1.14	0.26^b	2 (1.2)^c	2 (1.4)	− 1.15	0.25^b
Delusional memories	0 (0, 1.25)	0 (0.1)	− 1.02	0.31^b	0 (0.2)^c	0 (0.1)	− 0.77	0.44^b
PSQI score	8.40 ± 3.11	10.14 ± 4.19	− 2.29	0.02	8.22 ± 3.07	10.19 ± 4.52	− 2.31	0.02*
HADS
Anxiety score	3 (1.5)	4 (2.6)	− 1.65	0.10^b	3.10 ± 2.70	4.17 ± 3.00	− 1.70	0.09
Depression score	2.02 ± 2.61	2.98 ± 2.68	− 1.75	0.08	1.78 ± 2.53	3.05 ± 2.87	− 2.13	0.04*
SF-36 total score	120.62 ± 12.09	116.42 ± 15.03	1.50	0.14	120.85 ± 12.65	116.21 ± 16.19	1.45	0.15

Statistical analysis was performed using independent t test
PSQI Pittsburgh Sleep Quality Index, HADS Hospital Anxiety and Depression Scale, SF-36 the MOS 36-item Short-Form, mITT modified intention-to-treat, PTSD post-traumatic stress disorder, PP per-protocol;*P < 0.05
^aChi-squared test
^bMann-Whitney U test
^cn = 43

ISSN: 1364-8535