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Table 1 Baseline characteristics

From: Impact of protocolized diuresis for de-resuscitation in the intensive care unit

Parameter

Historical cohort (n = 273)

Intervention cohort (n = 91)

p value

Matching parameter demographics

 Age (years)a

58 (48–68)

58 (46–70)

0.711

 Male genderb

134 (49.1)

49 (53.8)

0.431

 Medicare payerc

134 (49.1)

43 (47.3)

0.935

 Medicaid payerc

97 (35.5)

36 (39.5)

 Commercial payerc

32 (11.7)

10 (10.9)

 Self-pay or government payerc

9 (3.3)

2 (2.2)

 Rural countyb

33 (12.1)

9 (9.8)

0.262

 Urban areab

105 (38.5)

28 (30.8)

 Urban clusterb

135 (49.5)

54 (59.3)

Non-matching parameter demographics

 Chronic kidney diseaseb

41 (15.0)

11 (12.1)

0.489

 Cirrhosisb

40 (14.7)

8 (8.8)

0.152

Matching critical illness parameters and comorbidities

 Cumulative fluid balance at furosemide start (mL)a

2243 (0–5381)

1411 (− 124–4438)

0.161

 Vasopressor utilization prior to furosemideb,d

119 (43.6)

49 (53.8)

0.89

 Time MV prior to furosemide (hours)a

45.5 (22–83)

52 (30.5–104)

0.155

 Diagnostic-related group weighta

5.1 (2.3–5.9)

5.6 (2.4–6.3)

0.167

 Prior SCr to furosemide (mg/dL)a

0.96 (0.74–1.29)

0.95 (0.75–1.44)

0.598

 Sequential Organ Failure Assessment score a

6 (4–8)

6 (4–8)

0.875

  Chronic obstructive pulmonary diseaseb

64 (23.4)

25 (27.5)

0.439

 Acute respiratory distress syndromec

16 (5.9)

3 (3.3)

0.425

 From emergency department (ED)c

65 (23.8)

14 (15.4)

0.301

 From outside hospitalc

96 (35.2)

39 (42.9)

 From outside hospital via EDc

62 (22.7)

25 (27.5)

 From other intensive care unitc

5 (1.8)

2 (2.2)

 From floorb

45 (16.5)

11 (12.1)

  1. MV mechanical ventilation
  2. aWilcoxon rank sum, median (interquartile range)
  3. bChi-square test; number (percentage)
  4. cFisher’s exact, number (percentage)
  5. dVasopressors including norepinephrine, epinephrine, or vasopressin