Fig. 3

The differential expression of HERV/MaLR according to the immune status of septic shock patients (discovery phase). a Principal component analysis developed from the HERV expression matrix. Healthy volunteers, patients with normal expression of mHLA-DR, and patients with low expression of mHLA-DR are indicated in gray, pink, and blue, respectively. b Venn diagrams from HERV/MaLR differential expression analyses, according to the day of sampling and mHLA-DR expression (compared between septic shock patient groups). Upregulated probesets are in green and downregulated probesets are in red. c The table shows the number of statistically significant differentially expressed loci (DELs) for HERV/MaLR, differentially expressed genes (DEGs), and the corresponding number of probesets, respectively. Downregulated loci are in red, upregulated loci are in green. For HERV/MaLR loci, the name, number of differentially expressed probesets (between brackets), and chromosomal locations (in italic) are indicated (GRCh38 genome version) for the five most differentially expressed loci. For genes, the official gene symbol and the number of differentially expressed probesets (between brackets) are indicated