Table 3 Clinical factors associated with the change in diaphragm thickness during assisted mechanical ventilation
|  | Unchanged during AMV (n = 33) | Recovery of thickness during AMV (n = 28) | p |
|---|---|---|---|
Age (years) | 53.2 ± 15.8 | 58.4 ± 14.4 | 0.187 |
Body weight (kg) | 76.4 ± 12.6 | 74.3 ± 13 | 0.524 |
BMI (kg/cm2) | 25.8 ± 3.3 | 25.4 ± 3.9 | 0.681 |
Chronic obstructive pulmonary disease, n (%) | 2/33 (6.1%) | 3/28 (10.7%) | 0.509 |
Diabetes, n (%) | 2/33 (6.1%) | 5/28 (17.9%) | 0.150 |
ARDS, n (%) | 14/33 (42.4%) | 11/28 (39.3%) | 0.804 |
Septic shock, n (%) | 3/33 (9.1%) | 7/28 (25.0%) | 0.094 |
NMBA (days) | 2 [0, 5.5] | 2 [0, 5] | 0.774 |
NMBA days on CMV days (%) | 28.6 [0, 75.7] | 30.4 [0, 85.6] | 0.803 |
Median SOFA during ICU admission | 4.6 [3.2, 5.9] | 4.3 [3.4, 5.3] | 0.606 |
TV/kg of ideal body weight | 6.9 [6.1, 7.8] | 7.4 [6.4, 8.5] | 0.152 |
Respiratory rate during AMV (bpm) | 19.2 ± 4 | 16.7 ± 3.2 | 0.019 |
Rapid Shallow Breathing Index (RR/TV, breaths/min/l) | 44 ± 13 | 37 ± 11 | 0.029 |
Peak pressure during AMV (cmH2O) | 17.9 ± 4.1 | 17.1 ± 4.1 | 0.441 |
Pressure support level (cmH2O) | 8.4 ± 2.4 | 7.6 ± 2.4 | 0.163 |
PEEP during AMV (cmH2O) | 8.9 ± 2.5 | 8.9 ± 2.4 | 0.984 |
Plateau pressure during AMV (cmH2O) | 20.1 ± 3.1 | 18.9 ± 3.9 | 0.225 |
Driving pressure during AMV (cmH2O) | 10.2 ± 2.6 | 9.5 ± 3 | 0.459 |
Compliance of respiratory system during AMV (cmH2O) | 52.5 ± 17.4 | 54.8 ± 14.4 | 0.618 |
Negative inspiratory force (cmH2O) | − 15.5 [− 21.8, − 8.4] | − 16.8 [− 26.5, − 11.5] | 0.451 |
Pressure Muscle Index (cmH2O) | 0.4 [0, 1.9] | 2 [0.5, 3] | 0.024 |
P0.1 (cmH2O) | 1.2 ± 0.8 | 1.8 ± 1.5 | 0.064 |
Thickening fraction (%) | 15 [8, 23.8] | 19.1 [9.2, 25.7] | 0.397 |
P/F during AMV | 242.3 ± 51 | 270 ± 82.1 | 0.159 |
pH during AMV | 7.46 [7.44, 7.48] | 7.45 [7.43, 7.48] | 0.397 |
Total water balance during AMV | − 5759 [− 9632, − 1348] | − 4884 [− 10742, − 2460] | 0.869 |
Prealbumin (mg/dl) | 18.8 [13.5, 26] | 22.5 [18.9, 24.4] | 0.438 |