Table 2 Clinical factors associated with the change in diaphragm thickness during controlled mechanical ventilation
|  | Unchanged during CMV (n = 29) | Thinning during CMV (n = 33) | p |
|---|---|---|---|
Age (years) | 56.0 ± 16.2 | 55.7 ± 14.8 | 0.945 |
Body weight (kg) | 78.9 ± 11.8 | 72 ± 12 | 0.033 |
BMI (kg/cm2) | 26.2 ± 3.3 | 25 ± 3.8 | 0.197 |
Chronic obstructive pulmonary disease, n (%) | 2/29 (6.9%) | 4/33 (12.1%) | 0.488 |
Diabetes, n (%) | 2/29 (6.9%) | 7/33 (21.2%) | 0.110 |
ARDS, n (%) | 10/29 (34.5%) | 15/33 (45.5%) | 0.380 |
Septic shock, n (%) | 6/29 (20.7%) | 5/33 (15.2%) | 0.569 |
NMBA (days) | 0 [0, 4] | 3 [0, 6.5] | 0.127 |
NMBA days on CMV days (%) | 28.7 [0, 56.6] | 35.7 [0, 83.8] | 0.456 |
Mean SOFA during ICU admission | 4.8 [3.4, 6.5] | 4.4 [3.3, 5.5] | 0.399 |
TV/kg of ideal body weight | 6.6 ± 1.4 | 6.7 ± 1.5 | 0.968 |
Respiratory rate during CMV (bpm) | 14 [11.5, 19.3] | 15 [11.5, 20.1] | 0.601 |
Peak pressure during CMV (cmH2O) | 26.4 ± 5.7 | 27.5 ± 5.7 | 0.518 |
PEEP during CMV (cmH2O) | 10.4 ± 4 | 12.6 ± 4 | 0.034 |
Plateau pressure during CMV (cmH2O) | 21.9 ± 3.9 | 23.9 ± 3.5 | 0.063 |
Driving pressure during CMV (cmH2O) | 10.6 ± 2.9 | 10.6 ± 1.9 | 0.948 |
Compliance of respiratory system during CMV (cmH2O) | 44.5 [32.5, 50] | 44.1 [32.4, 48.8] | 0.887 |
P/F during CMV | 212 [142, 261] | 189 [156, 236] | 0.527 |
pH during CMV | 7.42 ± 0.04 | 7.42 ± 0.02 | 0.476 |
Total water balance during CMV | 1699 [− 1109, 4240] | 1148 [− 1568, 3151] | 0.305 |
Prealbumin (mg/dl) | 23.4 ± 7.6 | 18.5 ± 6.6 | 0.050 |