From: Lactate kinetics in ICU patients using a bolus of 13C-labeled lactate
Volunteers (n = 6) | ICU, normal lactate (n = 6) | ICU, elevated lactate (n = 4) | |
---|---|---|---|
P-lactate [mmol/L] | 0.7 (0.4–0.9) | 0.8 (0.6–1.5) | 3.8 (2.1–4.9) |
Ra [μmol/kg/min] | 11.5 (8.5–18.5) | 14.5 (12.3–18.4) | 33.2 (27.3–44.2) |
Metabolic clearance [L/min] | 1.43 (1.22–2.27) | 1.30 (0.77–1.77) | 0.80 (0.57–1.17) |
Vc [L] | 9.0 (7.0–14.2) | 8.4 (5.3–13.5) | 10.3 (7.6–14.7) |