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Table 6 Effect of diuretic use on urine output test characteristics to predict successful discontinuation of RRT

From: Determining the optimal time for liberation from renal replacement therapy in critically ill patients: a systematic review and meta-analysis (DOnE RRT)

StudyCutoff Value# PatientsSensitivity (95% CI)Specificity (95% CI)AUROC (95% CI)
Jeon et al., diuretics [37]191 mL/day55781.2 (77.6, 84.5)71.6 (68.0, 75.0)0.821 (0.797, 0.845)
Jeon et al., diuretics (oliguric) [37]125 mL/day61972.1 (64.6, 78.8)68.8 (61.3, 75.7)0.745 (0.692, 0.798)
Raurich et al., no diuretics [27]178 mL/6 h420.73 (0.58, 0.89) before, 0.85(0.72, 0.99) after cessation
Raurich et al., diuretics [27]178 mL/6 h590.86 (0.76, 0.88) before, 0.94 (0.88, 1.0) after cessation
Uchino et al., no diuretics [21]436 mL/day33546.580.90.845 (0.799, 0.883)
Uchino et al., diuretics [21]2330 mL/day1940.671 (0.585, 0.750)
Yoshida et al., no diuretics [17]1810 mL/day2261.577.80.71 (0.46, 0.88)
Yoshida et al., diuretics [17]1720 mL/day3072.0100.00.84 (0.64, 0.94)