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Table 4 Adjusted logistic regression for dichotomized GOS (favorable outcome: GOS = 4 and 5, and unfavorable outcome: GOS < 4) for core model and extended model with and without the addition of PTCI. AUC and AIC for each model are represented along with the ANOVA comparison between the model with and without the addition of PTCI. We used Nahelkerke’s Pseudo R2 for consistency with the original IMPACT study

From: Impact of a posttraumatic cerebral infarction on outcome in patients with TBI: the Italian multicenter cohort INCEPT study

 Core modelExtended model
OR95% C.I.pOR95 C.I.p
Age1.031.01–1.060.0021.011.01–1.070.002
GCSm0.340.14–0.770.0120.331.27–7.140.015
Pupils2.761.08–7.350.0351.790.64–5.050.263
PTCI   4.521.88–11.39< 0.001
AUC0.73 (95% C.I.: 0.66–0.82)0.79 (95% C.I.: 0.71–0.83)
AUC comparisonModel with PTCI is better than the model without PTCI p = 0.0007
Nagelkerke’s R20.210.33
Age1.031.01–1.060.0031.031.01–1.060.004
GCSm0.290.12–0.070.0070.270.10–0.670.007
Pupils3.111.14–8.900.0272.090.68–6.480.190
Hypotension2.240.73–7.120.1603.290.99–11.600.055
Hypoxia1.580.41–6.010.4952.000.43–11.630.37
SAH1.230.49–3.190.6521.300.46–3.800.62
EDH0.930.28–0.410.8827.960.26–2.280.68
Marshall CT score0.9910.99
PTCI   6.842.58–19.7< 0.001
AUC0.74 (0.65–0.81)0.82 (0.69–0.85)
Nagelkerke’s R20.260.39
AUC comparisonModel with PTCI is better than the model without PTCI p = 0.00008
  1. GCSm Glasgow Coma Scale motor score, OR proportional odds ratio, C.I. confidence interval, SAH traumatic subarachnoid hemorrhage, EDH epidural hematoma. Hypotension and hypoxia refer to both pre-hospital and intra-hospital periods