From: Nutrition therapy in critical illness: a review of the literature for clinicians
Equation factors | Patient and system factors |
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• Sample size of the original equation • The characteristics of the original development population (including age, body composition, and disease state) • The population characteristics in which the equation is used • The addition of commonly used ‘injury’ or ‘stress’ factors • Using an adjusted body weight with the equation | • Individual patient heterogeneity in the metabolic response to critical illness • Differing body composition (fat-free mass and fat mass) • Changes in medical management over time in elements that impact metabolism (like surgery, pain, and sedation practices) |