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Table 1 Cohort characteristics and secondary outcomes

From: Variability in usual care fluid resuscitation and risk-adjusted outcomes for mechanically ventilated patients in shock

 w/ FRFw/o FRFLess-than-expected*ExpectedGreater-than-expectedAll
Count, no. (%)16,805 (49.7)17,026 (50.3)8502 (25.1)18,379 (54.3)6950 (20.5)33,831
Count with shock, no. (%)7967 (47.4)7003 (41.1)5033 (59.2)6284 (34.2)3653 (52.6)14,970 (44.2)
Age, mean ± SD, years66.6 ± 14.254.8 ± 18.859.6 ± 17.861.3 ± 17.660.5 ± 17.660.7 ± 17.7
Male gender, %50.654.555.050.954.152.6
Race, %
 White63.665.663.665.663.264.6
 Black18.714.816.817.016.016.8
 Other17.719.619.617.420.718.7
Comorbidities§, %
 Diabetes41.222.530.532.132.631.8
 CHF57.30.025.330.327.428.5
 Chronic pulmonary disease15.911.413.913.613.413.7
 Cerebrovascular disease0.10.10.10.10.10.1
 Dementia1.10.81.01.00.91.0
 Non-metastatic neoplasm6.17.07.06.07.36.5
 Metastatic neoplasm2.43.63.32.83.03.0
 Para and quadriplegia2.42.62.02.92.12.5
 Peripheral vascular disease8.82.95.86.05.65.9
 Rheumatic disease3.32.12.62.82.62.7
 Chronic renal disease39.92.520.721.420.721.1
 Mild liver disease3.65.55.03.85.84.5
 Major liver disease2.54.94.12.95.43.7
Admission organ dysfunctions§, %
 Respiratory100.0100.0100.0100.0100.0100.0
 Hematologic11.811.915.59.314.111.9
 CNS25.724.627.923.127.025.1
 Cardiac47.441.159.234.252.644.2
 Renal38.828.541.328.039.133.6
 Hepatic4.64.86.63.45.94.7
 Average per case, no.2.32.12.52.02.42.2
Secondary outcomes
 Hospital LOS7 (4–12)4 (2–9)5 (2–10)6 (3–10)6 (2–11)6 (2–10)
 ICU LOS4 (2–7)2 (1–5)3 (1–6)3 (2–6)3 (2–7)3 (2–6)
 Length of MV3 (2–7)2 (2–5)3 (2–6)3 (2–5)3 (2–6)3 (2–6)
 Cost in thousands, $18.5 (10.8–32.2)12.7 (7.2–24.0)15.0 (7.9–27.9)15.0 (8.5–26.7)17.9 (9.8–32.7)15.5 (8.6–28.2)
  1. FRF fluid reductive factor, LOS length of stay in days, MV mechanical ventilation
  2. *Less-than-expected = difference between observed and predicted day 1 fluids is less than − 1.5 L
  3. Expected = difference between observed and predicted day 1 fluids is between − 1.5 and 1.5 L
  4. Greater-than-expected = difference between observed and predicted day 1 fluids is more than 1.5 L
  5. §Patients may have one or more comorbidities or admission organ dysfunctions. Comorbidities selected from the Charlson-Deyo Comorbidity Index. Admission organ dysfunctions and respective definition codes adapted from Angus et al. [9]
  6. Secondary outcomes are presented as median (IQR)