Sublingual microcirculation does not reflect red blood cell transfusion thresholds in the intensive care unit—a prospective observational study in the intensive care unit

Table 3 Changes in microvascular flow index and proportion of perfused vessels before and after RBC transfusion

	MFI, median (IQR)		p value	PPV, median (IQR)		p value	TVD, median (IQR)		p value	PVD, median (IQR)		p value
	Before RBCT	After RBCT	p value	Before RBCT	After RBCT	p value	Before RBCT	After RBCT	p value	Before RBCT	After RBCT	p value
All	2.75 (2.33–2.91)	2.83 (2.60–2.91)	0.002	83.3 (70.5–89.7)	85.3 (78.4–90.0)	0.001	10.38 (9.51–11.62)	11.27 (10.23–12.45)	0.005	8.68 (6.95–9.74)	9.60 (8.35–10.46)	< 0.001
Septic	2.41 (2.00–2.77)	2.91 (2.91–3.00)	0.008	71.7 (66.3–85.3)	89.2 (86.4–92.6)	0.001
TTH 75 g/l	2.70 (2.33–2.91)	2.83 (2.64–2.91)	< 0.001	82.8 (67.9–89.6)	85.3 (79–89.5)	< 0.001
TTH 90 g/l	2.75 (2.41–2.62)	2.75 (2.5–2.91)	0.665	82.7 (71.6–88.4)	86.3 (74.5–91.3)	0.308

RBCT red blood cell transfusion, MFI microvascular flow index, IQR interquartile range, PPV proportion of perfused vessels, TVD total vessel density, PVD perfused vessel density, TTH transfusion threshold

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