H0 | H6 | ∆ H0–H6 (H6–H0) | p value** | |
---|---|---|---|---|
Heart rate (bpm) | 115 (110; 125) | 100 (92; 103) | − 18 (− 25; − 15) | 0.004 |
SAP (mmHg) | 110 (102; 117) | 103 (99; 104) | − 9 (− 14; 1) | 0.16 |
DAP(mmHg) | 54 (47; 55) | 55 (54; 59) | 4 (0; 8) | 0.12 |
MAP (mmHg) | 72 (68; 72) | 72 (67; 75) | 0 (− 3; 4) | 0.52 |
Double product (mm Hg.bpm) | 13,266 (12,138; 15,065) | 9682 (8736; 10,609) | − 2657 (− 3305; − 2628) | 0.008 |
CI(L/min/m2) | 4.2 (3.1; 4.4) | 2.9 (2.5; 3.7) | − 0.6 (− 1.2; − 0.5) | 0.004 |
SVi (mL/m2) | 29.8 (27.3; 37.8) | 28.2 (27.2; 36.5) | − 0.2 (− 5.2; − 0.0) | 0.25 |
CPI (W/m2 | 0.61 (0.54; 0.70) | 0.48 (0.40; 0.58) | − 0.10 (− 0.17; − 0.06) | 0.008 |
SVRi (dyn s m2 cm−5) | 1164 (1143; 1412) | 1379 (1333; 1876) | 190 (139; 427) | 0.004 |
CFI (1/min) | 6.1 (4.8; 7.4) | 3.7 (3.5; 4.8) | − 1.9 (− 2.6; − 1.0) | 0.004 |
EPLW(mL/kg) | 8 (7; 12) | 9 (8; 11) | 0 (− 1; 1) | 0.91 |
CVP (mmHg) | 8 (5; 8) | 8 (6; 12) | 1 (0; 2) | 0.58 |
GEF (%) | 20 (17; 21) | 17 (15; 19) | − 3 (− 3; − 2) | 0.004 |
Diuresis (mL/h) | 100 (50; 150) | 50 (10; 70) | − 60 (− 90; − 50) | 0.016 |
SvcO2 (%) | 73.6 (70.0; 87.0) | 75.3 (71.0; 77.0) | − 3.5 (− 7.0; 3.5) | 0.47 |
DO2i (ml/min/m−2) | 444 (333; 615) | 366 (319; 437) | − 68 (− 98; − 64) | 0.031 |
VO2i (ml/min/m−2) | 79 (61; 119) | 93 (72; 96) | − 6 (− 13; 16) | 0.84 |
Norepinephrine (µg/kg) | 29.7 (20.2–50) | 38.1 (18.1–66.5) | 10.4 (5.7–25.5) | 0.027 |