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Table 3 Relationship between baseline parameters and probability to have a late resumption of diaphragm electrical activity (after 24 h) during the study period

From: Duration of diaphragmatic inactivity after endotracheal intubation of critically ill patients

  Odds ratio (95% confidence interval) p value N
Univariate logistic models    
 Age (year) 0.958 (0.928–0.990) 0.0101 69
 Sex (ref. Female) 0.748 (0.286–1.962) 0.5557 69
Acute Physiologic Assessment and Chronic Health Evaluation (APACHE) II Scoring System (score) 0.975 (0.919–1.034) 0.3949 68
Body mass index, (kg/m2) 0.987 (0.936–1.040) 0.6146 67
Mode of ventilation (ref. assisted) 6.824 (0.776–60.040) 0.0835 69
PaO2/FiO2 (mmHg) 1.002 (0.997–1.007) 0.3904 63
Creatinine (µmol/L) 1.002 (0.998–1.005) 0.4109 69
Baseline acute kidney injury stage (ref. no acute kidney injury)    69
 1 0.439 (0.142–1.356) 0.1526  
 2 2.824 (0.266–30.021) 0.3894  
 3 2.196 (0.483–9.991) 0.3088  
Baseline bilirubin (µmol/L) 1.005 (0.988–1.022) 0.5666 68
Cause of intubation (ref. Neurologic)    65*
 Pulmonary 0.324 (0.086–1.217) 0.4076  
 Hemodynamic 0.250 (0.050–1.251) 0.2145  
Sedation analgesia score during the first 6 h (score) 0.732 (0.408–1.313) 0.2950 54
Use of sedative (ref. No) 25.833 (6.411–104.094) < .0001 69
Use of propofol (ref. No) 6.944 (2.412–19.994) 0.0003 69
Dose of propofol (1 mg/kg) 1.090 (1.031–1.151) 0.0022 69
Use of midazolam (ref. No) 17.231 (4.375–67.860) < .0001 69
Dose of midazolam (0.01 mg/kg) 1.026 (0.998–1.055) 0.0666 69
Use of fentanyl (ref. No) 8.100 (2.750- 23.855) 0.0001 69
Dose of fentanyl (1 mcg/kg) 1.073 (1.003–1.148) 0.0394 69
Multivariable logistic model    69
 Neuromuscular blocking agent use (ref. No) 2.658 (0.811–8.713) 0.1067 69
  1. *4 patients with other causes of intubation were excluded