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Table 4 Change in respiratory system mechanics from day-1 to day-14

From: Static compliance of the respiratory system in COVID-19 related ARDS: an international multicenter study

n = 108

Day 1

Day 14

P valuea

Positive end expiratory pressure (cmH2O), mean ± SD

11.8 ± 2.7

10.3 ± 2.8

 < 0.001

Plateau pressure (cmH2O), median (IQR)

23.5 (21–27)

23.5 (20–26.5)

0.49

Driving pressure (cmH2O), median (IQR)

11 (9–14)

13 (10–16)

 < 0.001

Tidal volume (ml/kg IBW), mean ± SD

6.2 ± 0.8

5.6 ± 1.5

 < 0.001

Crs (mL/cmH2O), mean

37.8 ± 11.4

31.2 ± 14.4

 < 0.001

  1. SD standard deviation, IQR interquartile range, IBW ideal body weight, Crs static compliance of the respiratory system
  2. aP value was calculated by paired t-test or Wilcoxon test as appropriate