Table 1 Patient characteristics
Control (n = 12) | Sepsis-AKI (n = 14) | |
|---|---|---|
Mean age (years) | 62 (20–79) | 76 (53–85) |
Sex (male:female) | 5:7 | 11:3 |
Comorbidities/medical history (n) | ||
Hypertension | 3 | 6 |
Diabetes mellitus | 1 | 1 |
COPD or asthma | 4 | 2 |
Coronary artery disease | 1 | 5 |
Renal disease | 0 | 0 |
Auto-immune disease | 0 | 1 |
Neoplasms (extra-renal) | 4 | 1 |
RIFLE stage (n) | N/A | |
Risk | 0 | |
Injury | 6 | |
Failure | 8 | |
Lost renal function | 0 | |
End-stage kidney failure | 0 | |
Need for RRT in ICU: yes/no | N/A | 5/14 |
Serum creatinine at admission (μmol/L) | N/A | 135 (81–355) |
Serum creatinine before biopsy (μmol/L) | 73 (58–114) | 156 (73–401) |
APACHE IV score | N/A | 97 (50–175) |
SAPS II score | N/A | 65 (35–88) |
Sepsis focus | N/A | |
Lower respiratory tract | 5 | |
Skin/soft tissue | 2 | |
Intra-abdominal (Mesenteric ischemia, necrotizing pancreatitis) | 6 | |
Endovascular (endocarditis) | 1 |