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Table 1 Patient characteristics

From: Sepsis is associated with mitochondrial DNA damage and a reduced mitochondrial mass in the kidney of patients with sepsis-AKI

  Control (n = 12) Sepsis-AKI (n = 14)
Mean age (years) 62 (20–79) 76 (53–85)
Sex (male:female) 5:7 11:3
Comorbidities/medical history (n)   
 Hypertension 3 6
 Diabetes mellitus 1 1
 COPD or asthma 4 2
 Coronary artery disease 1 5
 Renal disease 0 0
 Auto-immune disease 0 1
 Neoplasms (extra-renal) 4 1
RIFLE stage (n) N/A  
 Risk   0
 Injury   6
 Failure   8
 Lost renal function   0
 End-stage kidney failure   0
Need for RRT in ICU: yes/no N/A 5/14
Serum creatinine at admission (μmol/L) N/A 135 (81–355)
Serum creatinine before biopsy (μmol/L) 73 (58–114) 156 (73–401)
APACHE IV score N/A 97 (50–175)
SAPS II score N/A 65 (35–88)
Sepsis focus N/A  
 Lower respiratory tract   5
 Skin/soft tissue   2
 Intra-abdominal (Mesenteric ischemia, necrotizing pancreatitis)   6
 Endovascular (endocarditis)   1
  1. Data are presented as median with upper and lower range. N/A not applicable, RRT renal replacement therapy, ICU intensive care unit, APACHE Acute Physiology and Chronic Health Evaluation, SAPS Simplified Acute Physiology Score