Skip to main content

Table 1 Baseline characteristics of septic shock according to the culture results

From: Characteristics and clinical outcomes of culture-negative and culture-positive septic shock: a single-center retrospective cohort study

Characteristics

Total

(N = 1,718)

CNSS

(N = 706)

CPSS

(N = 1,012)

P

Age

66.0 (58.0–74.0)

66.0 (56.0–74.0)

68.0 (59.0–74.0)

0.02

Male

1,035 (60.2)

450 (63.7)

585 (57.8)

0.01

Past illness

    

 HTN

605 (35.2)

261 (37.0)

344 (34.0)

0.20

 DM

425 (24.7)

165 (23.4)

260 (25.7)

0.27

 CAD

182 (10.6)

72 (10.2)

110 (10.9)

0.66

 Pulmonary disease

108 (6.3)

49 (6.9)

59 (5.8)

0.36

 Malignancy

782 (45.5)

302 (42.8)

480 (47.4)

0.06

 Hematologic disorder

118 (6.9)

53 (7.5)

65 (6.4)

0.39

 CKD

238 (13.9)

128 (18.1)

110 (10.9)

 < 0.01

 LC

29 (1.7)

9 (1.3)

20 (2.0)

0.34

Initial vital signs

    

 SBP (mmHg)

91.0 (80.0–112.0)

90.0 (80.0–109.0)

93.0 (80.0–113.0)

0.28

 DBP (mmHg)

58.0 (50.0–69.0)

58.0 (50.0–68.0)

58.0 (50.0–71.0)

0.73

 PR (/min)

107.0 (89.0–125.0)

105.0 (88.0–123.0)

108.0 (90.0–126.0)

0.06

 RR (/min)

20.0 (20.0–24.0)

20.0 (20.0–24.0)

20.0 (20.0–22.0)

0.04

 BT (℃)

37.6 (36.6–38.7)

37.2 (36.5–38.2)

37.7 (36.7–38.9)

 < 0.01

Laboratory

    

 WBC (× 103/μL)

9.7 (5.0–15.9)

10.2 (5.5–16.2)

9.2 (4.7–15.7)

0.06

 Hemoglobin (g/dL)

10.7 (9.1–12.4)

10.7 (9.2–12.6)

10.7 (9.0–12.3)

0.30

PT (INR)

1.3 (1.1–1.5)

1.3 (1.1–1.4)

1.3 (1.1–1.5)

0.20

 Lactate (mmol/L)

2.9 (1.7–5.1)

2.5 (1.5–4.5)

3.2 (1.9–5.4)

 < 0.01

 BUN (mg/dL)

25.0 (17.0–38.0)

24.0 (17.0–39.0)

25.0 (17.0–37.0)

0.95

 Creatinine (mg/dL)

1.3 (0.9–2.1)

1.3 (0.9–2.2)

1.3 (0.9–2.1)

0.10

 Bilirubin (mg/dL)

1.1 (0.6–2.4)

0.9 (0.5–1.7)

1.3 (0.7–3.0)

 < 0.01

 Albumin (g/dL)

2.6 (2.2–3.1)

2.6 (2.2–3.1)

2.6 (2.2–3.1)

0.37

 CRP (mg/dL)

11.6 (5.0–19.8)

11.1 (4.6–19.2)

11.9 (5.3–20.2)

0.02

SOFA score

7.0 (5.0–10.0)

7.0 (5.0–10.0)

8.0 (6.0–10.0)

 < 0.01

Source control

653 (38.0)

202 (28.6)

451 (44.6)

 < 0.01

Antibiotics escalation

189 (11.0)

31 (4.4)

158 (15.6)

 < 0.01

  1. Data are presented as n (%) or mean with standard deviation
  2. Abbreviations: CNSS, culture negative septic shock; CPSS, culture positive septic shock; HTN, hypertension; DM, diabetes mellitus; CAD, coronary artery disease; CKD, chronic kidney disease; LC, liver cirrhosis; SBP, systolic blood pressure; DBP, diastolic blood pressure; PR, pulse rate; RR, respiratory rate; BT, body temperature; GCS, Glasgow Coma Scale; WBC, white blood cells; PT, prothrombin time; INR, international normalized ratio; BUN, blood urea nitrogen; CRP, C-reactive protein; and SOFA, sequential organ failure assessment