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Table 1 List of 23 articles included in systemic review and meta-analysis that reported on children with sepsis needing ECMO

From: Role of extracorporeal membrane oxygenation in children with sepsis: a systematic review and meta-analysis

S2tudy author

Year

Sample Size

Age (mean/median), (IQR, SD)

% male

Type of ECMO

Country/location

C. W. Lillehei et al

1989

8

Not Stated

Not Stated

Not Specified

USA (Children’s Hospital Boston)

S. McCune et al

1990

10

80hrs (37)

Not Stated

10 VA

USA (Children’s National Medical Center)

J. R. Hocker et al

1992

15

Not Stated

Not Stated

Not Specified

USA (Kosair Children’s Hospital)

D. Cochrane et al

1992

5

Not Stated

Not stated

5 VA

Australia (The Royal Children’s Hospital)

M. Nagaya et al

1993

7

0.74y (0.7–0.8)

Not Stated

7 VA

Japan (Central Hospital, Aichi)

J. Beca and W. Butt

1994

9

12y (0.2–15)

56

9 VA

Australia (The Royal Children’s Hospital)

A.P. Goldman et al

1997

12

Not Stated

Not Stated

10 VA, 2VV

Multi-center (Australia and UK)

D. K. Luyt et al

2004

11

1y (0.8–1.3)

Not Stated

7 VA, 4VV

UK (Glenfield Hospital, Leicester)

G. MacLaren et al

2007

45

2.5y (0.4–9)

62

45 VA

Australia (The Royal Children’s Hospital)

R. Tiruvoipati et al

2007

6

4y (0.17–14)

Not stated

2 VA, 4 VV

UK (Glenfield Hospital, Leicester)

S. J. Wu et al

2007

8

4.3y (2.9–63)

50

5 VA, 3 VV

Taiwan (Mackay Memorial Hospital)

S. Horton et al

2010

47

1.4y (0.1–7.5)

3.9y (0.5- 12.8)

63

67

35 Peripheral VA

12 Central VA

Australia (The Royal Children’s Hospital)

G. MacLaren et al

2011

23

6y (2.8–12.3)

57

23 Central VA

Australia (The Royal Children’s Hospital)

C. C. Peng et al

2012

12

4.7y (3.1)

58

8 VA, 4VV

Taiwan (Mackay Memorial Hospital)

Y. Kawai et al

2015

14

12y (4.2–15)

64

13 VA, 1 VV

USA (University of Michigan)

J. Rambaud et al

2015

22

2.5y (3.1)

64

22 VA

France (Armand-Trousseau Hospital)

A. Ruth et al

2015

1,858

1.1y (0.2–6.7)1

53

Not Specified

USA (Pediatric healthcare information system)

K. Y. Chen et al

2016

7

3.9y (0.4–12.8)2

Not Stated

Not Stated

Not Stated

Australia (Royal Children’s Hospital and Monash Medical Center)

A. Sole et al

2018

21

3.3y (0.7–4.7) P

1 day (1–5) N

62

21 VA

Spain (Hospital Sant Joan de Deu)

F. Oberender et al

2018

44

3.6y (0.5–8.0)

52

44 VA

Australia, New Zealand, Netherlands, UK, USA

T. H. Chang et al

2018

55

7.2y (6.2)

53

Not Specified

Taiwan (National Taiwan University Children’s Hospital)

K. Robb et al

2019

415

Not Stated

Not stated

Not specified

USA (National Inpatient Sample)

L.J. Schlapbach et al

2019

80

1.3y (0.1–7.0)

61

23 Peripheral VA

Australia & New Zealand (ANZPIC Registry)

     

57 Central VA

 
  1. Abbreviations: VA: Venoarterial, VV: Venovenous, Peripheral and Central refers to the type of cannulation for ECMO. P: pediatric Patients, N: Neonates, Data presented as mean ± SD, median (25th to 75th percentile), or median [range]. 1: Patients with ECMO-Only. 2 Patients with ECMO + RRT