Electrical impedance tomography to titrate positive end-expiratory pressure in COVID-19 acute respiratory distress syndrome

Table 4 Comparison of PEEP titration in supine versus prone position, for patients with coronavirus disease-19-related acute respiratory distress syndrome

	C-ARDS in supine position (n = 14)	C-ARDS in prone position (n = 14)	p value
PaO₂/FiO₂ (mmHg)	107 [93, 136]	179 [127, 190]	< 0.01
EIT-PEEP titration
Best PEEP^a (cmH₂O)	12 [9, 12]	12 [10, 15]	0.59
AUC for compliance	344 [316, 439]	455 [332, 494]	0.04
Hyperdistension at PEEP 18 cm H₂O (%)	24 [17, 30]	17 [15, 41]	0.63
AUC for hyperdistension	113 [68, 134]	80 [40, 194]	0.82
Collapse at PEEP 6 cm H₂O (%)	23 [19, 37]	35 [23, 42]	0.07
AUC for collapse	86 [58, 139]	173 [135, 261]	< 0.01

^aDefined using EIT as the smallest sum of hyperdistension and collapse. Continuous variables are expressed as median [interquartile range]
PEEP positive end-expiratory pressure, EIT electrical impedance tomography, AUC area under the curve in supine and prone position (see Fig. 4)

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