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Table 1 Patient characteristics of total cohort and subcohorts with and without thromboembolic events

From: Thromboembolic complications in critically ill COVID-19 patients are associated with impaired fibrinolysis

 

Cohort (n = 40)

Thromboembolic events (N = 23)

No thromboembolic events (N = 17)

p value

Age (years, (median, [IQR]))

67

[57.3–76.6]

66

[56–76]

68

[62–77.5]

ns

Gender, male (n, %)

35

87.5%

20

87%

15

88%

ns

BMI, kg/m2 (median, [IQR])

28.1

[24.8–32.8]

27.8

[24.2–33]

28.7

[25.7–32.3]

ns

Duration of ICU stay, days (median, [IQR])

39.5

[24–54.25]

42

[28–58]

25

[8.5–47.5]

0.05

Death during ICU stay (n, %)

11

27.5%

9

39.1%

2

11.8%

0.58

Intubation (n, %)

31

77.5%

20

87%

11

65%

ns

ECMO (n, %)

10

25%

9

39.1%

1

6%

ns

CRRT (n, %)

21

52.5%

16

69.6%

5

29.4%

0.013

SOFA score (median, [IQR])

9

[6.3–11.8]

10

[6–11]

8

[4.5–11]

ns

SIC score (median, [IQR])

3

[2–4]

3

[2–4]

3

[2–4]

ns

APACHE score (median, [IQR])

28

[22–33]

29

[23–34]

26

[19–31.8]

ns

Preexisting conditions

 Coronary artery disease (n, %)

9

22.5%

6

26%

3

18%

ns

 Hypertension (n, %)

25

62.5%

14

61%

11

65%

ns

 Diabetes mellitus/insulin resistance (n, %)

13

32.5%

10

43%

3

18%

ns

 Chronic kidney disease (n, %)

7

17.5%

6

26%

1

6%

ns

 Chronic dialysis (n, %)

1

2.5%

1

4%

0

0%

ns

 Lung disease (n, %)

7

17.5%

6

26%

1

6%

ns

  1. ECMO Extracorporeal membrane oxygenation, SOFA sequential organ failure assessment, CRRT continuous renal replacement therapy, SIC sepsis-induced coagulopathy, APACHE acute physiology and chronic health evaluation